Biomedical Sciences & Pathobiology Faculty

Bernard S. Jortner, VMD, MS, Diplomate, ACVP

Co-director, Laboratory for Neurotoxicity Studies
Professor Emeritus
Department of Biomedical Sciences & Pathobiology


  • 1969
    NIH, Neuropathology
    Yale University
    New Haven, CT
  • 1966
    MS, Comp. Pathology
    University of CT
    Storrs, CT
  • 1960 – 1962
    Residency, Pathology
    Bronx, NY Veterans Hospital
  • 1958
    VMD, Veterinary Medicine
    University of Pennsylvania
    Philadelphia, PA

Board Certification

  • 1963
    Diplomate, American College of Veterinary Pathologists

Research Interests

  • Dr. Jortner is interested in the neuropathological effects of toxins, in particular that of organophosphate compounds. Methods of study include light microscopy (with a focus on use of epoxy resin embedded tissue sections to allow high resolution study), morphometrics, electron microscopy and immunohistochemistry.
  • In collaboration with neurotoxicologist Dr. Marion Ehrich, Dr. Jortner has studied effects of heavy metals, solvents and in particular the delayed neurotoxicity of organophosphates. Their approach to the pathology of these states has employed high resolution light microscopy, transmission electron microscopy, immunohistochemistry (at the light and electron microscopic levels) and morphometry.
  • Other interests include pathological effects of toxins on tissues besides the nervous system and peripheral nerve pathology.

Professional Experience

  • 2010 – Present
    Professor Emeritus
    Virginia-Maryland College of Veterinary Medicine
    Virginia Tech
    Blacksburg, VA
  • 1980 – 2010
    Professor of Pathology
    Virginia-Maryland College of Veterinary Medicine
    Virginia Tech
    Blacksburg, VA
  • 1971 – 1980
    Associate Professor of Pathology
    University of Medicine and Dentistry of New Jersey
    New Jersey Medical School
    Newark, NJ
  • 1966 – 1971
    Assistant Professor of Pathology
    Yale University School of Medicine
    New Haven, CT

Professional Memberships

  • American Association of Neuropathologists
  • American Society for Investigative Pathology
  • International Academy of Pathology
  • American College of Veterinary Pathologists
  • Society of Toxicologic Pathologists
  • International Brain Research Organization
  • Society for Neuroscience
  • Society of Toxicology
  • Peripheral Nerve Society

Selected Publications

  1. Jortner BS. The return of the dark neuron. A histological artifact complicating contemporary neurotoxicologic evaluation. NeuroToxicology 27:628-634, 2006.
  2. BS Jortner, SK Hancock, J Hinckley, L Flory, L Colby, L Tobias, L Williams, M Ehrich. Neuropathological studies of rats following multiple exposure to tri-ortho-tolyl phosphate, chlorpyrifos and stress. Toxicologic Pathology 33, 378-385. 2005.
  3. D.S. Barber, M.F. Ehrich and B.S. Jortner. The effect of stress on the temporal and regional distribution of uranium in rat brain after acute uranyl acetate exposure. Journal of Toxicology and Environmental Health 68, 1-13, 2005.
  4. Lo Pachin R.M., Jortner B.S., Reid, M., Das, S.: g-Diketone central neuropathy: quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots. Toxicol. Applied Pharmacol. 193:29-46, 2003.