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Recent Referred Publications

258. Inzana, T.J., X.J. Meng, T. Opriessnig, and L. Ballweber. 2014.  Commercial Methods in Clinical Veterinary Microbiology. In: Mannual of Commercial Methods in Clinical Microbiology, 2nd edition.  American Society for Microbiology Press, Washington, DC

257. Gerber PF, Xiao CT, Cao D, X.J. Meng, and T. Opriessnig. 2014. Comparison of real-time reverse transcriptase (RT)-PCR assays for detection of swine hepatitis E virus in fecal samples. Journal of Clinical Microbiology.  In Press.

256. Gerber PF, L.G. Giménez-Lirola, P.G. Halbur, L. Zhou, X.J. Meng, Y. Fang, and T. Opriessnig. 2014. Comparison of commercial enzyme-linked immunosorbent assays and fluorescent microbead immunoassays for detection of antibodies against porcine reproductive and respiratory syndrome virus in boars. Journal of Virological Methods. 197:63-66.

255. Hemann M, N.M. Beach, X.J. Meng, P.G. Halbur, and T. Opriessnig. 2014. A live-attenuated and an inactivated chimeric porcine circovirus (PCV) vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age. Canadian Journal of Veterinary Research. 78(1):8-16.

254. Ni YY, Z. Zhao, T. Opriessnig, S. Subramaniam, L. Zhou, D. Cao, Q. Cao, H. Yang, and X.J. Meng. 2014. Computer-aided codon-pairs deoptimization of the major envelope GP5 gene attenuates porcine reproductive and respiratory syndrome virus. Virology. 450-451:132-139.

253. Wang L, D. Cao, C. Wei, X.J. Meng, X. Jiang, and M. Tan.  2014. A dual vaccine candidate against norovirus and hepatitis E virus. Vaccine. 32:445-452.

252. Huang YW, A.W. Dickerman, P. Pineyro, L. Li, L. Fang, R. Kiehne, T. Opriessnig, and X.J. Meng. 2013. Origin, evolution, and genotyping of emergent porcine endemic diarrhea virus (PEDV) strains in the United States.  mBio. 4(5):e00737-13. doi:10.1128/mBio.00737-13.

251. Yugo DM and X.J. Meng.  2013. Hepatitis E Virus: Foodborne, Waterborne and Zoonotic Transmission. International Journal of Environmental Research and Public Health. 10:4507-4533.

250. Yin SH, Gerbera PF, Xiao CT, Beach NM, X.J. Meng, Halbur PG, and T. Opriessnig. 2013. Concurrent porcine circovirus type 2a (PCV2a) or PCV2b infection increases the rates of amino acid mutations of porcine reproductive and respiratory syndrome virus (PRRSV) during serial passages in pigs. Virus Research.  2013:178(2):445-51.

249. Owolodun OA, Giménez-Lirola LG, Gerber P, Sanford BJ, Feagins AR, X.J. Meng, Halbur PG, and T. Opriessnig. 2013. Development of a fluorescent microbead-based immunoassay for the detection of hepatitis E virus IgM and IgG antibodies in pigs and comparison to an enzyme-linked immunoassay. Journal of Virological Methods. 193:278-283.

248. Zhou L, Y.Y. Ni, P. Piñeyro, C.M. Cossaboom, S. Subramaniam, B.J. Sanford, B.A. Dryman, Y.W. Huang, and X.J. Meng. 2013. Broadening the heterologous cross-neutralizing antibody inducing ability of porcine reproductive and respiratory syndrome virus by breeding the GP4 or M genes. PLoS ONE. 8(6):e66645. doi:10.1371/journal.pone.0066645.

247. Meng XJ, and HL Shivaprasad. 2013. Avian hepatitis E virus infections. In: Swayne DE et al (eds) Diseases of Poultry, 13th Edition. Blackwell Publishing Press. pp. 494-512.

246.  Meng XJ. 2013. Hepatitis E Virus: Structural and Molecular Biology. In: Viral Hepatitis, 4th edition. Howard C. Thomas, Anna SF Lok, Stephen A. Locarnini, and Arie Zuckerman (eds). Wiley-Blackwell. pp 419-430.

245. Meng XJ. 2013. Hepatitis E. In: Kaslow RA, Stanberry LA and LeDuc JW (eds). Viral Infections in Humans: Epidemiology and Control, 5th Edition. Springer Publishing.

244. Ni YY, T. Opriessnig, L. Zhou, D. Cao, Y.W. Huang, P.G. Halbur, and X.J. Meng. 2013. Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of the virus envelope genes from genetically divergent strains. Journal of Virology. 87:304-313.

243. Opriessnig T, K. O’Neill, P. Gerber, A. M. Gomes de Castro, L. G. Gimenéz-Lirola, N.M. Beach, L. Zhou, X.J. Meng, C. Wang, P.G. Halbur. 2013. A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection. Vaccine. 31:487-94.

242. Gerber PF, K. O’Neill, O. Owolodun, C. Wang, K. Harmon, J. Zhang, P.G. Halbur, L. Zhou, X.J. Meng, and T. Opriessnig. 2013. Comparison of commercial real-time RT-PCR kits for reliable, early and rapid detection of different heterologous strains of porcine reproductive and respiratory syndrome virus (PRRSV) in experimentally infected or negative boars using different sample types (semen, oral fluids, serum, blood swabs). Journal of Clinical Microbiology. 51(2):547-56.

241. Meng XJ. 2013. Zoonotic and foodborne transmission of hepatitis E virus.  Seminars in Liver Diseases33(1):41-49.

240. Meng XJ. 2013. Circoviridae. In: Fields Virology, 6th Edition. David M. Knipe and Peter M. Howley (eds). Lippincott Williams & Wilkins, Philadelphia, PA. pp1792-1801.

239. Meng XJ. 2013. Porcine circovirus: Pathogenesis and interaction with the immune system.  Annual Review of Animal Biosciences. 1:43-64.

238. Sanford, B.J., S.U. Emerson, R.H. Purcell, R.E. Engle, B.A. Dryman, T.E. Cecere, V. Buechner-Maxwell, D.P. Sponenberg, and X.J. Meng. 2013. Serological evidence for a hepatitis E virus (HEV)-related agent in goats in the United States. Transboundary and Emerging Diseases. 60(6):538-545.

237. Hu, J., Ni, Y., X.J. Meng, Zhang, C. 2012. Expression and purification of a chimeric protein consisting of the ectodomains of M and GP5 proteins of porcine reproductive and respiratory syndrome virus (PRRSV). Journal of Chromatography B. 911: 43-48.

236. Cossaboom CM, L. Córdoba, D. Cao, Y.Y. Ni, and X.J. Meng. 2012. Complete genome sequence of hepatitis E virus from rabbits in the United States. Journal of Virology. 86:13124-13125.

235. Zhou L, Yan-Yan Ni, Pablo Piñeyro, Brenton J. Sanford, Caitlin M. Cossaboom, Dian-Jun Cao, Yao-Wei Huang, and X.J. Meng. 2012. DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain. Virology. 434:96-109.

234. Córdoba L, Alicia R. Feagins, Tanja Opriessnig, Caitlin M. Cossaboom, Barbara A. Dryman, Yao-Wei Huang, and X.J. Meng. 2012. Rescue of a genotype 4 human hepatitis E virus (HEV) from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs. Journal of General Virology. 93(Pt 10):2183-2194.

233. Kwon H.-M., H.-W. Sung, and X.J. Meng. 2012. Serological prevalence, genetic identification and characterization of the first strains of avian hepatitis E virus from chickens in Korea. Virus Genes. 45:237-245.

232. Cecere TE, X.J. Meng, K. Pelzer, S. M. Todd, N. M. Beach, Y.Y. Ni, and T. LeRoith. 2012. Co-infection of porcine dendritic cells with porcine circovirus type 2a (PCV2a) and genotype II porcine reproductive and respiratory syndrome virus (PRRSV) induces CD4(+)CD25(+)FoxP3(+) T cells in vitro. Veterinary Microbiology. 160(1-2):233-239.

231. Huang YW, K.K. Harrall, B.A. Dryman, T. Opriessnig, E.M. Vaughn, M.B. Roof, and X.J. Meng. 2012. Serological profile of Torque teno sus virus species 1 (TTSuV1) in pigs and antigenic relationships between two TTSuV1 genotypes (1a and 1b), between two species (TTSuV1 and 2), and between porcine and human anelloviruses. Journal of Virology. 86(19):10628-10639.

230. Cao D, and X.J. Meng. 2012. Molecular biology and replication of hepatitis E virus. Emerging Microbes & Infections. (2012) 1, e17; doi:10.1038/emi.2012.7.

229. Sanford, B.J., T. Opriessnig, S.P. Kenney, B.A. Dryman, Córdoba L, and X.J. Meng. 2012. Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs. Vaccine. 30(44): 6249-6255.

228. Cossaboom CM, L. Córdoba, B.J. Sanford, P. Pineyro, B.A. Dryman, Y. Wang, and X.J. Meng. 2012. Cross-species infection of pigs with a novel rabbit, but not rat, strain of hepatitis E virus isolated in the United States. Journal of General Virology. 93:1687-1695.

227. Hemann H, H.G. Shen, N.M. Beach, X.J. Meng, P.G. Halbur, and T. Opriessnig. 2012. Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model. Veterinary Research Communications. 36:187-193.

226. Xiao CT, L.G. Giménez-Lirola, Y.W. Huang, X.J. Meng, P.G. Halbur, T. Opriessnig. 2012. The prevalence of Torque teno sus virus (TTSuV) is common and increases with the age of growing pigs in the United States. Journal of Virological Methods. 183(1):40-4.

225. Sinha A, K. Lin, M. Hemann, H. Shen, N.M. Beach, C. Ledesma, X.J. Meng, C. Wang, P. G. Halbur, and T. Opriessnig. 2012. ORF1 but not ORF2 dependent differences are important for in vitro replication of PCV2 in porcine alveolar macrophages singularly or coinfected with PRRSV. Veterinary Microbiology. 158(1-2):95-103.

224. Opriessnig T, P.C. Gauger, K.S. Faaberg, H. Shen, N.M. Beach, X.J Meng, C. Wang, P.G. Halbur. 2012. Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model. Veterinary Microbiology. 158(1-2):69-81.

223. Hemann M, N.M. Beach, X.J. Meng, P.G. Halbur, T. Opriessnig. 2012. Vaccination with inactivated or live-attenuated chimeric PCV1-2 results in decreased viremia in challenge-exposed pigs and may reduce transmission of PCV2. Veterinary Microbiology. 158(1-2):180-6.

222. Huang YW, A.R. Patterson, T. Opriessnig, B.A. Dryman, A. Gallei, K.K. Harrall, E.M. Vaughn, M.B. Roof, and X.J. Meng. 2012. Rescue of a porcine anellovirus (Torque teno sus virus 2) from cloned genomic DNA in pigs. Journal of Virology. 86:6042-6054.

221. Kenney S.P., R.S. Pudupakam, Y.W. Huang, F.W. Pierson, T. LeRoith, and X.J. Meng. 2012. The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release. Journal of Virology. 86(10):5637-46.

220. Karpe Y.A., and X.J. Meng. 2012. Hepatitis E virus replication requires an active ubiquitin-proteasome system. Journal of Virology. 86(10):5948-52.

219. Meng XJ. 2012. Emerging and re-emerging swine viruses. Transboundary and Emerging Diseases. 59 (Suppl. 1):85-102.

218. Meng XJ. 2012. Editorial: Spread like a wildfire--the omnipresence of porcine circovirus type 2 (PCV2) and its association with diseases. Virus Research. 164:1-3.

217. Hu J, Y.Y. Ni, B.A. Dryman, X.J. Meng, and C. Zhang. 2012. Plant-made oral subunit vaccine against porcine reproductive and respiratory syndrome virus (PRRSV) is immunogenic in mice. Vaccine. 30:2068-2074.

216. Meng X.J., P.G. Halbur, T. Opriessnig. 2012. Hepatitis E virus infection in swine. In: Jeffrey J. Zimmerman, Locke A. Karriker, Alejandro Ramirez, Kent J. Schwartz, Gregory W. Stevenson (eds): Diseases of Swine, 10th Edition. John Wiley & Sons, Inc. pp 554-556.

215. Kumar D, Beach N.M., X,J, Meng, and Hegde N.R. 2012. Use of PCR-based assays for the detection of the adventitious agent porcine circovirus type 1 (PCV1) in vaccines, and for confirming the identity of cell substrates and viruses used in vaccine production. Journal of Virological Methods. 179(1):201-211.

214. Beach NM, and Meng XJ. 2012. Porcine circovirus type 2 (PCV2): current vaccine efficacy and future vaccine development. Virus Research. 164:33-42.

213. Meng X.J., D.A. Anderson, V.A. Arankalle, S.U. Emerson, T.J. Harrison, S. Jameel, and H. Okamoto. 2012. Hepeviridae. In: Virus Taxonomy, 9th Report of the ICTV. King AMQ, M.J. Adams, E.B. Carstens, and E.J. Lefkowitz (eds), Elsevier Academic Press, London. pp 1021-1028.

212. Opriessnig T, J. Gomes-Neto, M. Hemann, H. Shen, N.M. Beach, Y.W. Huang, P.G. Halbur, and X.J. Meng. 2011. An experimental live chimeric porcine circovirus 1-2a vaccine is efficacious at decreasing porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model. Microbiology and Immunology. 55(12):863-73.

211. Dong C, J. Meng, X. Dai, J.H. Liang, A. R. Feagins, X.J. Meng, N. M. Belfiore, C. Bradford, J. L. Corn, C. Cray, G. E. Glass, M.L. Gordon, R.A. Hesse, D.L. Montgomery, W. L. Nicholson, A.A. Pilny, S. Ramamoorthy, D.D. Shaver, M. A. Purdy, H.A. Fields, S. Kamili, and C.G. Teo. 2011. Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States. Journal of Clinical Microbiology. 49(12):4164-4172.

210. O'Neill KC, H.G. Shen, K. Lin, M. Hemann, N.M. Beach, X.J. Meng, P.G. Halbur, and T. Opriessnig. 2011. Studies on PCV2 vaccination of 5-day-old piglets. Clinical and Vaccine Immunology. 18:1865-1871.

209. Beach NM, L. Córdoba, S.P. Kenney, and X.J. Meng. 2011. Productive infection of human hepatocellular carcinoma cells by porcine circovirus type 1. Vaccine. 29:7303-7306.

208. Cossaboom CM, L. Córdoba, B.A. Dryman, and X.J. Meng. 2011. Hepatitis E Virus in Rabbits, Virginia USA. Emerging Infectious Diseases. 17(11):2047-2049.

207. Pudupakam, R.S., S. P. Kenney, L. Córdoba, Y. W. Huang, B. A. Dryman, T. LeRoith, F.W. Pierson, and X.J. Meng. 2011. Mutational analysis of the hypervariable region of the hepatitis E virus reveals its involvement in the efficiency of viral RNA replication. Journal of Virology. 85:10031–10040.

206. Ni, Y.Y., Y.W. Huang, D.J. Cao, T. Opriessnig, and X.J. Meng. 2011. Establishment of a DNA-launched infectious clone for a highly pneumovirulent strain of type 2 porcine reproductive and respiratory syndrome virus: Identification and in vitro and in vivo characterization of a large spontaneous deletion in the nsp2 region. Virus Research. 160;264-273.

205. Meng X.J. 2011. From barnyard to food table: The omnipresence of hepatitis E virus and risk for zoonotic infection and food safety. Virus Research. 161:23-30.

204. Krawczynski, K., X.J. Meng, and J. Rybczynska. 2011. Pathogenetic elements of hepatitis E and animal models of HEV infection. Virus Research. 161(1):78-83.

203. Sinha, H.G. Shen, S. Schalk, N.M. Beach, Y.W. Huang, X. J. Meng, P.G. Halbur, and T. Opriessnig. 2011. Porcine reproductive and respiratory syndrome virus (PRRSV) influences infection dynamics of porcine circovirus type 2 (PCV2) subtypes PCV2a and PCV2b by prolonging PCV2 viremia and shedding. Veterinary Microbiology. 152(3-4):235-46.

202. Opriessnig T, H. Shen, N. Pal, S. Rmamoorthy, Y.W. Huang, K.M. Lager, N.M. Beach, P.G. Halbur, and X.J. Meng. 2011. A live-attenuated chimeric PCV2 vaccine is transmitted to contact pigs but is not upregulated by concurrent infection with PPV and PRRSV and is efficacious in a PCV2a-PRRSV-PPV challenge model. Clinical and Vaccine Immunology. 18(8):1261-8.

201. Baylis SA, Hanschmann KM, Blümel J, Nübling CM, and HEV Collaborative Study Group (Bouwknegt M, Rutjes S, Gärtner T, Kamili S, Drobeniuc J, Ijaz S, Izopet J, Kar P, Laue T, Matsubayashi K, Meldal B, Candotti D, Meng XJ, Mohn U, Nitsche A, Kaiser M, Pisani G, Marino F, Shih JW, Xiang GS, Thomas I, Uchida S, Wang Y, Geng Y, Wenzel J, Jilg W, Yu MY, Ma L). 2011. Standardization of hepatitis E virus (HEV) nucleic acid amplification technique-based assays: an initial study to evaluate a panel of HEV strains and investigate laboratory performance. Journal of Clinical Microbiology. 49(4):1234-1239.

200. Zhang H, U. Mohn, J.R. Prickett, S. Schalk, M. Motz, P.G. Halbur, A.R. Feagins, X.J. Meng, T. Opriessnig. 2011. Differences in capabilities of different enzyme immunoassays to detect anti-hepatitis E virus immunoglobulin G in pigs infected experimentally with hepatitis E virus genotype 3 or 4 and in pigs with unknown exposure. Journal of Virological Methods. 175(2):156-162.

199. Opriessnig T, D. Patel, R. Wang, P. G. Halbur, X.J. Meng, D. A. Stein, Y.J. Zhang. 2011. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Research. 91:36-42.

198. Opriessnig T, D.M. Madson, S. Schalk, S. Brockmeier, H.G. Shen, N.M. Beach, X.J. Meng, R.B. Baker, E.L. Zanella, and P.G. Halbur. 2011. Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae. Theriogenology. 76(2):351-360.

197. Sanford, B.J., Dryman BA, Huang YW, Feagins AR, LeRoith T, and X.J. Meng. 2011. Prior infection of pigs with a genotype 3 swine hepatitis E virus (HEV) protects against subsequent challenges with homologous and heterologous genotypes 3 and 4 human HEV. Virus Research. 159:17-22.

196. Huang YW, Harrall KK, Dryman BA, Beach NM, Kenney SP, Opriessnig T, Vaughn EM, Roof MB, aand X.J. Meng. 2011. Expression of the putative ORF1 capsid protein of Torque teno sus virus 2 (TTSuV2) and development of Western blot and ELISA serodiagnostic assays: correlation between TTSuV2 viral load and IgG antibody level in pigs. Virus Research. 158:79-88.

195. Opriessnig T., D.M. Madson, M. Roof, S.M. Layton, S. Ramamoorthy, X.J Meng, P.G. Halbur. 2011. Experimental reproduction of porcine circovirus type 2 (PCV2)-associated enteritis in pigs infected with PCV2 alone or concurrently with Lawsonia intracellularis or Salmonella typhimurium. Journal of Comparative Pathology. 145(2-3):261-70.

194. Cordoba L, Y.W. Huang, T. Opriessnig, K.K. Harrall, N.M. Beach, C. Finkielstein, S.U. Emerson, and X.J. Meng. 2011. Three amino acid mutations (F51L, T59A and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation. Journal of Virology. 85(11):5338-5349.

193. Beach NM, S.M. Smith, S. Ramamoorthy, and X.J. Meng. 2011. Chimeric porcine circoviruses (PCV) containing amino acid epitope tags in the C-terminus of the capsid gene are infectious and elicit both anti-epitope tag antibodies and anti-PCV2 neutralizing antibodies in pigs. Journal of Virology. 85:4591-4595.

192. Meng XJ. 2011. Hepatitis E virus. In: Oxford Textbook of Zoonoses, Second Edition. Biology, Clinical Practice, and Public Health Control. S.R. Palmer, Lord Soulsby, P.R. Torgerson, and David W.G. Brown (eds). Oxford University Press, Oxford, UK. pp 475-483.

191. Alberti KA, M.J. Estienne, X.J. Meng. 2011. Effect of vaccination of boars against porcine circovirus type 2 on ejaculate characteristics, serum antibody titers, viremia, and semen virus shedding. Journal of Animal Sciences. 89:1581-1587.

190. Feagins A.R., L. Cordoba, B.J. Sanford, B.A. Dryman, Y.W. Huang, S.U. Emerson, and X.J. Meng. 2011. Intergenotypic chimeric hepatitis E viruses (HEV) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs. Virus Research. 156; 141-146.

189. Patterson A.R., Johnson J. K., Ramamoorthy S, Hesse R.A., Murtaugh M.P., Pogranichniy R.M., Erickson G.A., Carman S, Hause B, X.J. Meng, and Opriessnig T. 2011. Inter-laboratory comparison of PCV2 indirect immunofluorescent assay and ELISA results on experimentally infected animals. Journal of Veterinary Diagnostic Investigation. 23(2):206-12.

188. Patterson AR, N.M. Juhan, D.M. Madson, X.J. Meng, P.G. Halbur and T. Opriessnig. 2011. Shedding and infection dynamics of porcine circovirus type 2 (PCV2) after experimental infection. Veterinary Microbiology. 149(1-2):91-8.

187. Opriessnig T, J.R. Prickett, D.M. Madson, H. Shen, N.M. Juhan, R.R. Pogranichniy, X.J. Meng, and P.G. Halbur. 2011. Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: Virological, serological, pathological and clinical effects in growing pigs. Veterinary Research. 41(3):31.

186. Xia H, N. Wahlbergc, S. Beláka, X.J. Meng, and L. Liu. 2011. The emergence of genotypes 3 and 4 hepatitis E virus in swine and humans: a phylogenetic perspective. Archives of Virology. 156:121-124.

185. Ramamoorthy S., T. Opriessnig, N. Pal, F.F. Huang, and X.J. Meng. 2011. Effect of an interferon-stimulated response element (ISRE) mutant of porcine circovirus type 2 (PCV2) on PCV2-induced pathological lesions in a porcine reproductive and respiratory syndrome virus (PRRSV) co-infection model. Veterinary Microbiology. 147:49–58.

184. Kwon H.M., T. LeRoith, R.S. Pudupakam, F.W. Pierson, Y.W. Huang, B.A. Dryman, and X.J. Meng. 2011. Construction of an infectious cDNA clone of avian hepatitis E virus (avian HEV) recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens. Veterinary Microbiology. 147:310-319.

183. Sinha A, H.G. Shen, S. Schalk, N.M. Beach, Y.W. Huang, P.G. Halbur, and X.J. Meng, T. Opriessnig. 2010. Porcine reproductive and respiratory syndrome virus (PRRSV) infection at the time of porcine circovirus type 2 (PCV2) vaccination has no impact on vaccine efficacy. Clinical and Vaccine Immunology. 17(12):1940-1945.

182. Beach N.M., Ramamoorthy S, Opriessnig T, Wu S.Q, and X.J. Meng. 2010. Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtypes in pigs. Vaccine. 29:221-232.

181. Shen HG, N. Beach, Y.W. Huang, P.G. Halbur, X.J. Meng, T. Opriessnig. 2010. Comparison of commercial and experimental porcine circovirus type 2 (PCV2) vaccines using a triple challenge with PCV2, porcine reproductive and respiratory syndrome virus (PRRSV), and porcine parvovirus (PPV). Vaccine. 28(37):5960-5966.

180. Cao D, Y.W. Huang, X.J. Meng. 2010. The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus (HEV) genome are critical for virus replication. Journal of Virology. 84(24):13040–13044.

179. Huang Y.W., and X.J. Meng. (2010). Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus (PRRSV). Virus Research. 154:141-149.

178. Opriessnig T, A.R. Patterson, D.M. Madson, N. Pal, S. Ramamoorthy, X.J. Meng, and P.G. Halbur. 2010. Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination. Veterinary Microbiology. 142(3-4):177-83.

177. Huang YW, B.A. Dryman, K.K. Harrall, E.M. Vaughn, M.B. Roof, and X.J. Meng. 2010. Development of SYBR green-based real-time PCR and duplex nested PCR assays for quantification and differential detection of species- or type-specific porcine Torque teno viruses (TTV). Journal of Virological Methods. 170:140–146.

176. Ziemer CJ, Bonner JM, Cole D, Vinjé J, Constantini V, Goyal S, Gramer M, Mackie R, Meng XJ, Myers G, Saif LJ. 2010. Fate and transport of zoonotic, bacterial, viral, and parasitic pathogens during swine manure treatment, storage, and land application. Journal of Animal Sciences. 88(13 Suppl):E84-94.

175. Beach N.M., N.M. Juhan, L. Cordoba, and X.J. Meng. 2010. Replacement of the replication factors of porcine circovirus (PCV) type 2 with those of PCV type 1 greatly enhances viral replication in vitro. Journal of Virology. 84:8986-8989.

174. Hu J, Ni Y, Dryman BA, Meng XJ, Zhang C. 2010. Purification of porcine reproductive and respiratory syndrome virus from cell culture using ultrafiltration and heparin affinity chromatography. Journal of Chromatography A. 1217;3489–3493.

173. Meng XJ. 2010. Recent advances in hepatitis E virus. Journal of Viral Hepatitis. 17; 153-161. (Invited review).

172. Pavio N, X.J. Meng, and C. Renou. 2010. Zoonotic hepatitis E: animal reservoirs and emerging risks. Veterinary Research. 41:46. (Invited review).

171. Huang YW, Y.Y. Ni, B.A. Dryman, and X.J. Meng. 2010. Multiple infection of porcine Torque teno virus in a single pig and characterization of the full-length genomic sequences of four U.S. prototype PTTV strains: Implication for genotyping of PTTV. Virology. 396:289-297.

170. Juhan NM, T. LeRoith, T. Opriessnig, and X.J. Meng. 2010. The open reading frame 3 (ORF3) of porcine circovirus type 2 (PCV2) is dispensable for virus infection but evidence of reduced pathogenicity is limited in pigs infected by a ORF3-null PCV2 mutant. Virus Research. 147:60-66.

169. Meng XJ. 2010. Hepatitis E virus: zoonotic risk and animal reservoirs. Veterinary Microbiology. 140:256-265. (Invited review).

168. Madson DM, S. Ramamoorthy, C. Kuster, N. Pal, X.J. Meng, P.G. Halbur, T. Opriessnig. 2009. Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars. Veterinary Research. 40(1):10.

167. Gillespie J, T. Opriessnig, X.J. Meng, K. Pelzer, and V. Maxwell. 2009. A review of Porcine circovirus type 2 and porcine circovirus associated disease. Journal of Veterinary Internal Medicine. 23(6):1151-63.

166. Beach N, R.B. Duncan, C.T. Larsen, X.J. Meng, N. Sriranganathan and F W Pierson. 2009. Persistent infection of turkeys with an avirulent strain of turkey hemorrhagic enteritis virus. Avian Diseases. 53(3):370-375.

165. Huang Y.W., Y. Fang, and X. J. Meng. 2009. Identification and characterization of a porcine monocytic cell line supporting porcine reproductive and respiratory syndrome virus (PRRSV) replication and progeny virion production by using an improved DNA-launched PRRSV reverse genetics system. Virus Research. 145:1–8.

164. Beach NM, Duncan RB, Larsen CT, X.J. Meng, Sriranganathan N, Pierson FW. 2009. Comparison of twelve Turkey hemorrhagic enteritis virus isolates allows for prediction of genetic factors affecting virulence. Journal of General Virology. 90:1978-1985.

163. Madson DM, Patterson AR, Ramamoorthy S, Pal N, X.J. Meng, and Opriessnig T. 2009. Effect of natural or vaccine-induced porcine circovirus type 2 (PCV2) immunity on fetal infection after artificial insemination with PCV2 spiked semen. Theriogenology. 72(6):747-54.

162. Ramamoorthy S., F.F. Huang, Y.W. Huang, and X.J. Meng. 2009. Interferon-mediated enhancement of in vitro replication of porcine circovirus type 2 (PCV2) is influenced by an interferon stimulated response element in the PCV2 genome. Virus Research. 145:236-243.

161. Billam P., T. LeRoith, R.S. Pudupakam, F.W. Pierson, R.B. Duncan, and X.J. Meng. 2009. Comparative pathogenesis in specific-pathogen-free chickens of two strains of avian hepatitis E virus recovered from a chicken with Hepatitis-Splenomegaly syndrome and from a healthy chicken, respectively. Veterinary Microbiology. 139(3-4):253–261.

160. Huang YW, and X. J. Meng. 2009. Identification of a porcine DC-SIGN-related C-type lectin, porcine LSECtin, and its order of intron removal during splicing: Comparative genomic analyses of the CD23/LSECtin/DC-SIGN gene clusters among mammalian species. Developmental and Comparative Immunology. 33:747–760.

159. Madson, DM, A.R. Patterson, S. Ramamoorthy, N. Pal, X.J. Meng, and T. Opriessnig. 2009. Effect of porcine circovirus type 2 (PCV2) vaccination of the dam on PCV2 replication in utero. Clinical and Vaccine Immunology. 16(6):830-834.

158. Peralta B, M. Biarnés, G. Ordóñez, R. Porta, M. Martín, E. Mateu, S. Pina, X.J. Meng. 2009. Evidence of widespread infection of avian hepatitis E virus (avian HEV) in chickens from Spain. Veterinary Microbiology. 137(1-2):31-6.

157. Meng XJ, D.S. Lindsay, and N. Sriranganathan. 2009. Wild Boars as Sources for Infectious Diseases in Livestock and Humans. Philosophical Transactions of the Royal Society B (Biological Sciences). 364:2697-2707.

156. Pudupakam RS, Y.W. Huang, P. Billam, S. Ramamoorthy, F.W. Pierson, and X.J. Meng. 2009. The hypervarible region (HVR) in the ORF1 of the hepatitis E virus (HEV) is dispensable for virus replication in vivo. Journal of Virology. 83(1):384-95.

155. Opriessnig T, A.R. Patterson, D.M. Madson, N. Pal, M. Rothschild, D. Kuhar, J. Lunney, N.M. Juhan, X.J. Meng, P.G. Halbur. 2009. Difference in severity of porcine circovirus type 2 (PCV2)-induced pathological lesions and diseases between selected Landrace and Pietrain pigs. Journal of Animal Sciences. 87(5):1582-90.

154. Madson DM, Patterson AR, Ramamoorthy S, Pal N, Meng XJ, and Opriessnig T. 2009. Reproductive failure experimentally induced in sows via artificial insemination with semen spiked with porcine circovirus type 2 (2). Veterinary Pathology. 46(4):707-16.

153. Opriessnig T., A. R. Patterson, D. Jones, N. M. Juhan, X. J. Meng, and P. G. Halbur. 2009. Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions. Canadian Journal of Veterinary Research. 73(2):81-86.

152. Huang YW, B. Dryman, and X. J. Meng. 2009. Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics. Developmental and Comparative Immunology. 33:464–480.

151. Opriessnig T., A.R. Patterson, X.J. Meng, P.G. Halbur. 2009. Porcine circovirus type 2 in muscle and bone marrow is infectious and transmissible to naïve pigs by oral consumption. Veterinary Microbiology. 133(1-2):54–64.

150. Ramamorthy S., and X.J. Meng. 2009. Porcine Circovirus: A Minuscule yet Mammoth Paradox. Animal Health Research Reviews. 10(1):1–20.

149. Gillespie J, N.M. Juhan, J. DiCristina, K.F. Key, S. Ramamoorthy, and X.J. Meng. 2008. A genetically-engineered chimeric vaccine against porcine circovirus type 2 (PCV2) is genetically stable in vitro and in vivo.  Vaccine. 26;4231–4236.

148. Meng XJ. 2008. Hepatitis E virus (hepevirus). Encyclopedia of Virology (5 vols), 3rd edition. B.W.J. Mahy and M.H.V. van Regenmortel (eds). Oxford: Elsevier. pp377-383.

147. Billam P, F.W. Pierson, W. Li, T. LeRoith, R. Duncan, and X.J. Meng. 2008. Development and Validation of a Negative Strand-Specific RT-PCR Assay for Detection of a Chicken Strain of Hepatitis E Virus: Identification of Non-Liver Replication Sites. Journal of Clinical Microbiology. 46:2630-2634.

146. Patterson AR, Johnson J, Ramamoorthy S, Meng XJ, Halbur PG, Opriessnig T. 2008. Comparison of three enzyme-linked immunosorbent assays to detect porcine circovirus type 2 (PCV2)-specific antibodies after vaccination or inoculation of pigs with distinct PCV1 or PCV2 isolates. Journal of Veterinary Diagnostic Investigation. 20(6):744-51.

145. Opriessnig T, S. Ramamoorthy, D.. Madson, A. Patterson, N. Pal, S. Carman, X.J. Meng, P.G. Halbur. 2008. Differences in virulence among porcine circovirus  type 2 isolates are unrelated to cluster type 2a or 2b and prior infection provides heterologous protection. Journal of General Virology. 89(10):2482-2491.

144. Madson D.M., S. Ramamoorthy, C. Kuster, N. Pal, X.J. Meng, P.G. Halbur, T. Opriessnig. 2008. Characterization of shedding patterns of porcine circovirus type 2a and type 2b in experimentally inoculated mature boars. Journal of Veterinary Diagnostic Investigation. 20(6):725-34.

143. Feagins A.R., T. Opriessnig, Y.W. Huang, P. G. Halbur, and X. J. Meng. 2008. Cross-species infection of specific-pathogen-free pigs by a genotype 4 strain of human hepatitis E Virus. Journal of Medical Virology. 80(8):1379-1386.

142. Guo H., E.M. Zhou, Z.F. Sun, and X.J. Meng. 2008. Immunodominant epitopes mapped by synthetic peptides on the capsid protein of avian hepatitis E virus (avian HEV) are non-protective.  Viral Immunology. 21(1):61-67.

141. N. Pal, Y.W. Huang, D.M. Madson, C. Kuster, X.J. Meng, P.G. Halbura, and T. Opriessnig. 2008. Development of a duplex real-time PCR assay for the simultaneous detection and quantification of porcine circovirus type 2 and an internal control on porcine semen samples.  Journal of Virological Methods. 149;217-225.

140. Anjan Purkayastha, Oswald Crasta, J. Dana Eckart, Michael Czar, X.J. Meng, Joan Setubal, Bruno Sobral (2008). Bioinformatics Resources for the Study of Viruses at the Virginia Bioinformatics Institute. In Structure-Based Study of Viral Replication. R.Holland Cheng, Tatsuo Miyamura eds. World Scientific Publishing Co. Pte. Ltd, Singapore/London-UK/Hackensack-NJ. pp.267-287. pp. 267-288.

139. Feagins AR, T. Opriessnig, D.K. Guenette, P.G. Halbur, and X.J. Meng. 2008. Inactivation of infectious hepatitis E virus in commercial pig livers.  International Journal of Food Microbiology. 123; 32-37.

138. Opriessnig T., Patterson AR, Elsener J, Meng XJ, Halbur PG.  2008. Influence of porcine circovirus type 2 (PCV2) maternal antibodies on efficacy of PCV2 vaccination to protect pigs from experimental infection with PCV2.  Clinical and Vaccine Immunology. 15(3):397-401.

137. Matanin M, Y.W. Huang, X.J. Meng, and C. Zhang. 2008. Purification of the major envelop protein GP5 of porcine reproductive and respiratory syndrome virus (PRRSV) from native virions. Journal of Virological Methods. 147:127-135.

136. Patel D., T. Opriessnig, D.A. Stein, P.G. Halbur, X.J. Meng, P.L. Iversen, and Y.-J. Zhang. 2008. Arginine-rich Cell Penetrating Peptide-conjugated Morpholino Oligomers Inhibit Porcine Reproductive and Respiratory Syndrome Virus Replication in vitro. Antiviral Research. 77:95-107.

135. Zhou E, Guo H., F. F. Huang, Z. F. Sun, X.J. Meng. 2008. Identification of two neutralization epitopes on the capsid protein of avian hepatitis E virus (avian HEV) by epitope mapping. Journal of General Virology. 89(2):500-508.

134. Meng XJ, HL Shivaprasad, and C Payne. 2007. Hepatitis E virus infections. In: M. Saif et al (eds) Disease of Poultry, 12th Edition. Blackwell Publishing Press. pp. 443-452.

133. Thomas PJ, T. Opriessnig, Juhan NM, Meng XJ, Halbur PG. 2007. Planned exposure through serum injection is not effective in preventing porcine circovirus type 2 (PCV2) infection and PCV2 associated disease (PCVAD) and lesions. Journal of Swine Health and Production. 15(6):330-338.

132. Oprissnig T, X.J. Meng, and P.G. Halbur. 2007. Porcine circovirus type 2 associated disease (PCVAD): Update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies. Journal of Veterinary Diagnostic Investigation. 19(6):591-615.

131. Key KF, DiCristina J, Gillespie J, Guenette DK, and Meng XJ (2007). Direct inoculation of RNA transcripts from an infectious cDNA clone of porcine reproductive and respiratory syndrome virus (PRRSV) into the lymph nodes and tonsils of pigs initiates PRRSV infection in vivo. Archieves of Virology. March 15, 2007 ePub ahead of print.

130. Martín M., J. Segalés, F.F. Huang, D.K. Guenette, E. Mateu, N. de Deus, and X.J. Meng (2007). Association of hepatitis E virus (HEV) and postweaning multisystemic wasting syndrome (PMWS) with lesions of hepatitis in pigs. Veterinary Microbiology. Jan 3 [Epub ahead of print].

129. Guo H., E. M. Zhou, Z. F. Sun, and X.J. Meng. 2007. Egg whites from eggs of chickens infected experimentally with avian hepatitis E virus contain infectious virus, but evidence of complete vertical transmission is lacking. Journal of General Virology. 88:1532-1537.

128. Billam P, Sun ZF, and Meng XJ (2007). Analysis of the complete genomic sequence of an apparently avirulent strain of avian hepatitis E virus (avian HEV) identified major genetic differences compared with the prototype pathogenic strain of avian HEV. Journal of General Virology. 88:1538-1544

127. Huang YW, Oprissnig T, Halbur PG, and Meng XJ (2007). Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivo. Journal of Virology. 81:3018-3026.

126. Feagins A.R., T. Opriessnig, D.K. Guenette, P.G. Halbur, and X.J. Meng (2007). Detection and characterization of infectious hepatitis E virus from commercial pig livers sold in local grocery stores in the United States. Journal of General Virology. 88:912-917.

125. Guo H, E.M. Zhou, Z.F. Sun, and X.J. Meng (2007). Protection of chickens against avian hepatitis E virus (avian HEV) infection by immunization with recombinant avian HEV capsid protein. Vaccine. 25:2892-2899.

124. Snyder. E.E., Kampanya, N., Lu, J., Nordberg, E., Rajasimha, H.K., Shukla, M., Soneja, J., Tian, Y., Xue, T., Yoo, H., Zhang, F., Dharmanolla, C., Dongre, N.V., Gillespie, J., Hamelius, J., Hance, M., Huntington, K., Jukneliene, D., Koziski, J., Mackasmiel, L., Mane, S.P., Nguyen, V., Purkayastha, A., Shallom, J., Yu, G., Gabbard, J., Hix, D., Azad, A., Baker, S., Boyle, S., Khudyakov, Y., Meng, X.J., Rupprecht, C., Vinje, J., Crasta, O.R., Czar, M.J., Dickerman, A., Eckart, J.D., Kenyon, R., Will, R., Setubal, J.C. and Sobral, B. 2007. PATRIC: The VBI PathoSystems Resource Integration Center. Nucleic Acids Research. 35:D401-6.

123. Opriessnig T, N.E. McKeown, E. Zhou, X.J. Meng, P.G. Halbur (2006). Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence. Journal of General Virology. 87:2923-2932.

122. Opriessnig T., N.E. McKeown, K.L. Harmon, X.J. Meng, and P.G. Halbur (2006). Porcine circovirus type-2 infection decreases the efficacy of a modified live porcine reproductive and respiratory syndrome virus vaccine. Clinical and Vaccine Immunology. 13:923-929.

121. Zhang Y, Stein DA, Fan SM, Wang KY, Kroeker AD, X.J. Meng, Iversen PL, and Matson DO (2006). Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers. Veterinary Microbiology. 117:117-129.

120. Opriessnig T., M. Fenaux, P. Thomas, M. J. Hoogland, R. B. Evans, M. F. Rothschild, X.J. Meng, and P. G. Halbur (2006). Evidence of breed-dependent differences in susceptibility to porcine circovirus type 2-associated disease and lesions. Veterinary Pathology. 43:281-293.

119. Opriessnig, T., P. G. Halbur, S. Yu, E. L. Thacker, M. Fenaux, and X. J. Meng (2006). Effects of the timing of administration of Mycoplasma hyopneumnia bacterin on development of lesions associated with porcine circovirus type 2. Veterinary Record. 158:149-154.

118. Jothikumar N. J., T. Cromeans, B. Robertson, X.J. Meng, and V.R. Hill1 (2006). A broadly reactive one step real-time RT-PCR assay for rapid and sensitive detection of hepatitis E virus (HEV). Journal of Virological Methods. 131:65-71.

117. Guo H., E. M. Zhou, Z. F. Sun, XJ Meng, and P.G. Halbur. 2006. Identification of B cell epitopes in the capsid protein of avian hepatitis E virus (avian HEV) that are common to human and swine HEVs or unique to avian HEV. Journal of General Virology. 87:217-223.

116. Huang FF, Pierson FW, Toth TE, and XJ Meng (2005). Construction and characterization of infectious cDNA clones of a chicken strain of hepatitis E virus (HEV), avian HEV. Journal of General Virology. 86:2585-2593.

115. McKeown NE, T. Opriessnig, P. Thomas, D. K. Guenette, F. Elvinger, M. Fenaux, P.G. Halbur, and X.J. Meng (2005). Effects of type 2 porcine circovirus (PCV2) maternal antibodies on experimental infection of piglets with PCV2. Clinical and Diagnostic Laboratory Immunology. 12:1347-1351.

114. Kasorndorkbua C, Opriessnig T, Huang F.F., Guenette D.K., Thomas P.J., X.J. Meng, and P.G. Halbur (2005). Infectious swine hepatitis E virus is present in pig manure storage facilities on United States farms, but evidence of water contamination is lacking. Applied and Environmental Microbiology. 71:7831-7837.

113. Meng X.J., and P.G. Halbur (2005). Porcine lymphotropic herpesviruses. In: Diseases of Swine, 9th Edition. pp.550-554. Blackwell Publishing/Iowa State University Press, Ames, Iowa.

112. Meng X.J., and P.G. Halbur (2005). Swine hepatitis E virus. In: Diseases of Swine, 9th Edition. pp.537-545. Blackwell Publishing/Iowa State University Press, Ames, Iowa.

111. Meng X.J., F. Elvinger, P.G. Halbur, and C.A. Wilson (2005). Miscellaneous viral infections. In:Diseases of Swine, 9th Edition. pp.537-560. Blackwell Publishing/Iowa State University Press, Ames, Iowa.

110. Meng XJ (2005). Hepatitis E as a zoonosis. Viral Hepatitis, 3rd edition, Edited by H. Thomas, A. Zuckermann, and S. Lemon. pp611-623. Blackwell Publishing Ltd, Oxford, U.K.

109. Cooper K., F.F. Huang, L. Batista, C.D. Rayo, J.C. Bezanilla, T.E. Toth, and X. J. Meng (2005). Identification of genotype 3 hepatitis E virus (HEV) in serum and fecal samples from pigs in Thailand and Mexico, where genotype 1 or 2 HEV strains are prevalent in respective human populations. Journal of Clinical Microbiology. 43(4):1684-1688.

108. Billam P., F.F. Huang, Z.F. Sun, F.W. Pierson, R.B. Duncan, F. Elvinger, D.K. Guenette, T.E. Toth, and X. J. Meng (2005). Systematic pathogenesis and replication of avian hepatitis E virus in specific-pathogen-free adult chickens.Journal of Virology. 79(6):3429-37.

107. Meng X.J. (2005). Hepatitis E virus: Cross-species infection and zoonotic risk. Clinical Microbiology Newsletter. 26(6):43-48.

106. Huang Y.W., G. Haqshenas, C. Kasorndorkbua, P. G. Halbur, S. U. Emerson, X.J. Meng (2005). Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication-competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs. Journal of Virology. 79:1552-1558.

105. Emerson, S.U., Anderson, D., Arankalle, A., X.J. Meng, Purdy, M., Schlauder, G.G. and Tsarev, S.A. (2004). Hepevirus. In: Virus Taxonomy, VIIIth Report of the ICTV. Fauquet C.M., M.A. Mayo, J. Maniloff, U. Desselberger, and L.A. Ball (eds), pp851-855. Elsevier/Academic Press, London.

104. Fenaux M., T. Opriessnig, P. G. Halbur, Y. Xu, B. Potts, and X.J. Meng (2004). Detection and in vitro and in vivo characterizations of porcine circoviruses from porcine-derived commercial pepsin product. Journal of General Virology. 85:3377-3382.

103. Kasorndorkbua C., D.K. Guenette, F.F. Huang, P.J. Thomas, X.J. Meng, and P.G. Halbur (2004). Routes of transmission of swine hepatitis E virus in pigs. Journal of Clinical Microbiology. 42:5047-5052.

102. Fenaux M, T. Opriessnig, P.G. Halbur, F. Elvinger, and X.J. Meng (2004). Two amino acid mutations in the capsid protein of type 2 porcine circovirus (PCV2) enhanced PCV2 replication in vitro and attenuated the virus in vivo. Journal of Virology. 78:13440-13446.

101. McKeown N.E., M. Fenaux, P.G. Halbur, X.J. Meng (2004). Molecular characterization of porcine TT virus, an orphan virus, in pigs from six different countries. Veterinary Microbiology. 104:113-117.

100. Opriessnig T., E.L. Thacker, S. Yu, M. Fenaux, X.J. Meng, P.G. Halbur (2004). Experimental reproduction of postweaning multisystemic wasting syndrome in pigs by dual infection with Mycoplasma hyopneumoniae and porcine circovirus type 2. Veterinary Pathology. 41(6):624-640.

99. Lekcharoensuk P, I. Morozov, P.S. Paul, N. Thangthumniyom, W. Wajjawalku, and X.J. Meng (2004). Epitope mapping of the major capsid protein of type 2 porcine circovirus (PCV2) using chimeric PCV1 and PCV2 viruses. Journal of Virology. 78:8135-8145.

98. Sun Z.F., C.T. Larsen, F. F. Huang, P. Billam, F. W. Pierson, T. E. Toth, and X.J. Meng (2004). Generation and infectivity titration of an infectious stock of avian hepatitis E virus (HEV) in chickens and cross-species infection of turkeys with avian HEV. Journal of Clinical Microbiology. 42:2658-2662.

97. Sun Z.F., and X.J. Meng (2004). Antigenic Cross-reactivity between the Nucleocapsid Protein of SARS Coronavirus and Polyclonal Antisera of Antigenic Group I Animal Coronaviruses: Implication for SARS Diagnosis. Journal of Clinical Microbiology. 42:2351-2352.

96. Fenaux M, T. Opriessnig, P.G. Halbur, F. Elvinger, and X.J. Meng (2004). A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV2 Cloned Into the Genomic Backbone of the Non-Pathogenic PCV1 Induces Protective Immunity Against PCV2 Infection in Pigs. Journal of Virology. 78:6297-6303.

95. Huang FF, Z.F. Sun, S.U. Emerson, R.H. Purcell, H.L. Shivaprasad, F.W. Pierson, T.E. Toth, and X.J. Meng (2004). Determination and analyses of the complete genomic sequence of avian hepatitis E virus and attempts to experimentally infect rhesus monkeys with avian HEV. Journal of General Virology.  85:1609-1618.

94. Sun ZF, C. Larsen, A. Dunlop, F. Huang, F. Pierson, T. Toth, and X.J. Meng (2004). Genetic identification of avian hepatitis E virus (avian HEV) from healthy chicken flocks and characterization of the capsid gene of 14 avian HEV isolates from chickens with hepatitis-splenomegaly syndrome in different geographic regions of the United States. Journal of General Virology.  85:693-700.

93. Opriessnig T, M. Fenaux, J. M. Gallup, S. Yu, R. B. Evans, D. Cavanaugh, F. J. Pallares, M. R. Ackermann, E. Thacker, K. M. Lager, X.J. Meng, and P. G. Halbur (2004). Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus. Veterinary Microbiology. 98:209-220.

92. Fenaux, M., T. Opriessnig, P.G. Halbur, X.J. Meng (2003). Immunogenicity and pathogenicity of the chimeric infectious DNA clones between pathogenic type 2 porcine circovirus (PCV2) and non-pathogenic PCV1 in weaning pigs. Journal of Virology. 77:11232-11243.

91. Key, K.F., D.K. Guenette, K.J. Yoon, P.G. Halbur, T.E. Toth, and X.J. Meng (2003). Development of a heteroduplex mobility assay to identify field isolates of porcine reproductive and respiratory syndrome virus with nucleotide sequences closely related to those of modified live-attenuated vaccines. Journal of Clinical Microbiology. 41:2433 -2439.

90. Kasorndorkbua, C., B.J. Thacker, P.G. Halbur, D.K. Guenette, R. Beitenwerf, R. L. Royer, and X.J. Meng (2003). Experimental infection of swine hepatitis E virus in pregnant gilts. Canadian Journal of Veterinary Research. 67:303-306.

89. Opriessnig T, Yu S, Gallup J.M., Evans R.B., Fenaux M, Pallares F, Thacker E.L., Brockus C.W., Ackermann M.R., Thomas P, Meng X.J., and Halbur P.G. (2003). Effect of vaccination with selective bacterins on conventional pigs infected with type 2 porcine circovirus. Veterinary Pathology. 40:521-529.

88. Sun, Z.F., F.F. Huang, P.G. Halbur, S.K. Schommer, F.W. Pierson, T.E. Toth, and X.J. Meng (2003). Use of heteroduplex mobility assays (HMA) for pre-sequence screening and identifications of variant strains of avian and swine hepatitis E viruses. Veterinary Microbiology. 96:165-176.

87. Meng, X.J. (2003). Swine hepatitis E virus: cross-species infection and risk in xenotransplantation. Current Topics in Microbiology and Immunology . 278:185-216.

86. Engle RE, Yu C, Emerson SU, Meng X.J., and Purcell RH (2002).  Hepatitis E virus (HEV) capsid antigen derived from virus of human or swine origin is equally efficient for detecting anti-HEV by enzyme immunoassay.  Journal of Clinical Microbiology. 40:4576-4580.

85. Opriessnig T., P.G. Halbur, K.J. Yoon, R.M. Pogranichniy, E.M. Vaughn, K.M. Harmon, R.Evans, K.F. Key, F.J. Pallares, P. Thomas, X.J. Meng (2002). Comparison of molecular and biological characteristics of a modified live PRRSV vaccine (RespPRRS/Repro™), the parent strain of the vaccine (ATCC VR2332), ATCC VR2385, and two recent field isolates of PRRSV. Journal of Virology. 76:11837-11844.

84. Huang FF, G.Haqshenas, D.K. Guenette, P.R. Woolcock, H.L. Shrivaprasad, C.T. Larsen, F.W. Pierson, T.E. Toth, X.J. Meng (2002).Heterogeneity and seroprevalence of the newly-identified avian hepatitis E virus from chickens in the United States. Journal of Clinical Microbiology. 40:4197-4202.

83. Halbur PG, Pallares FJ, Rathje JA, Evans R, Hagemoser WA, Paul PS, and X.J. Meng (2002). Effects of different U.S. isolates of porcine reproductive and respiratory syndrome virus (PRRSV) on blood and bone marrow parameters of experimentally infected pigs. Veterinary Record  151:344-348.

82. Huang, F.F., G.Haqshenas, D.K. Guenette, P.G. Halbur, S.Schommer, F.W. Pierson, T.E. Toth and X.J. Meng (2002).Detection by RT-PCR and genetic characterization of field isolates of swine hepatitis E virus from pigs in different geographic regions of the U.S.  Journal of Clinical Microbiology. 40:1326-1332.

81. Haqshenas G., F.F. Huang, M. Fenaux, D.K. Guenette, F.W. Pierson, H.L. Shivaprasda, T.E. Toth  and X.J. Meng(2002).  The putative capsid protein of the newly identified avian hepatitis E virus shares antigenic epitopes with that of swine and human hepatitis E viruses and the chicken big liver and spleen disease virus.  Journal of General Virology.  83:2201-2209.

80.  Fenaux, M., P.G. Halbur, G. Haqshenas,R. Royer, P. Nawagitgul,M. Gill,  T.E. Toth, and X.J. Meng (2002).  The cloned genomic DNA of the type-2 porcine circovirus (PCV-2) is infectious when injected into the liver and lymph nodes of SPF pigs: characterization of clinical course, virus distribution and pathological lesions.  Journal of Virology76:541-551.

79. Kasorndorkbua, C., P.G. Halbur, D.K. Guenette, T.E. Toth, X.J. Meng (2002). Use of a swine bioassay and a RT-PCR assay to assess the risk of transmission of swine hepatitis E virus in pigs.  Journal of Virological Methods101:71-78.

78. Wu, J.C., CM Chen, TY Chiang, WH Tsai, WJ Jeng, IJ Sheen, JY Chen,CC Lin, X.J. Meng (2002).Potential Subclinical spread of HEV among swine, swine handlers and different countries: a longitudinal study.Journal of Medical Virology66:488-492.

77.  Inzana, T.J., D.S. Lindsay, X.J. Meng, and K.W. Post (2002). Commercial Methods in Clinical Veterinary Microbiology.   In: Mannual of Commercial Methods in Clinical Microbiology.  American Society for Microbiology Press, Washington, DC. pp. 336-359.

76. Meng X.J., B. Wiseman, D. Guenette, R. A. Robinson, R.E. Engle, S. U. Emerson, R. H. Purcell, and T. E. Toth (2002). Prevalence of antibodies to the hepatitis E virus in veterinarians working with swine and in normal blood donors of the United States and other countries.  Journal of Clinical Microbiology. 40:117-122.

75. Emerson SU, Zhang M, Meng X.J., St. Clair M, Nguyen H, Huang Y, and Purcell RH (2001).  Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element. Proceedings of the National Academy of Sciences USA    98:15270-15275.

74. Haqshenas G. and X.J. Meng (2001). Determination of the nucleotide sequences of the extreme 3' and 5' ends of the swine hepatitis E virus genome.  Archives of Virology. 146:2461-2467.

73. Williams, T., Kasorndorkbua C., Halbur P.G., Guenette D., Toth T.E., X.J. Meng(2001).  Evidence for extrahepatic sites of replication of the hepatitis E virus in a swine model.   Journal of Clinical Microbiology39(9):3040-3046.

72.Key, K.F., Haqshenas G, Guenette D., S.L. Swenson, T.E. Toth, X.J. Meng (2001). Genetic characterization of the major envelope gene of acute porcine reproductive and respiratory syndrome virus isolates.Veterinary Microbiology. 83(3):249-263.

71.  Haqshenas, G., H.L. Shivaprasad, P. Woolcock, D. Read, X.J. Meng (2001).  Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-spleenomegaly syndrome.Journal of General Virology82:2449-2462.

70.  Halbur, P.G., C. Kasorndorkbua, C. Gilbert, D. Guenette, M. B. Potters, R. H. Purcell, S. U. Emerson, T.E. Toth, X.J. Meng (2001).  Comparative pathogenesis of infections of growing pigs with hepatitis E viruses recovered from a swine and a human.  Journal of Clinical Microbiology39:918-923.

69. Meng, X.J. (2000).  Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development.  Veterinary Microbiology. 74:309-329.

68. Meng, X.J (2000).Novel strains of hepatitis E virus identified from humans and other animal species: Is hepatitis E a zoonosis?Journal of Hepatology  33:842-845.

67.  Fenaux, M., P.G. Halbur, M. Gill, T.E. Toth, and X.J. Meng (2000). Genetic characterization of type-2 porcine circovirus (PCV-2) from pigs with PMWS in different geographic regions of North America and development of a differential PCR-RFLP assay to detect and differentiate infections between PCV-1 and PCV-2. Journal of Clinical Microbiology   38:2494-2503.

66.Meng, X.J. (2000).  Zoonotic and xenozoonotic risks of the hepatitis E virus.   Infectious Disease Review.   2:35-41.

65.  Meng, X.J., S. Dea, R.E. Engle, R. Friendship, Y.S. Lyoo, T. Sirinarumitr, K. Urairong, D. Wang, D. Wong, D. Yoo, Y. Zhang, R.H. Purcell, and S.U. Emerson (1999).Prevalence of antibodies to the hepatitis E virus (HEV) in pigs from countries where hepatitis E is common or rare in the human population.  Journal of Medical Virology59:297-302.

64.  Kabrane-Lazizi, Y., X.J. Meng, R.H. Purcell, and S.U. Emerson.  Evidence that the genomic RNA of hepatitis E virus is capped (1999).Journal of Virology.73:8848-8850.

63.  Hsieh, S.-Y., X.J. Meng, Y.-H. Wu, A.W. Tam, S.-T. Liu, D.-Y. Lin, and Y.-F. Liaw (1999).  Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with the Taiwan isolates of human hepatitis E virus.  Journal of Clinical Microbiology37:3828-3834.

62.Kabrane-Lazizi, Y., J.B. Fine, J. Elm, G.E. Glass, H. Higa, A. Diwan, C.J. Gibbs Jr, X.J. Meng, S.U. Emerson, R.H. Purcell (1999).Evidence for wide-spread infection of wild rats with hepatitis E virus in the United States.  American Journal of Tropical Medicine and Hygiene.61:331-335.

61.  Meng, X.J., P.G. Halbur, M. Shapiro, S. Govindarajan, J.D. Bruna, I. K. Mushahwar, R.H. Purcell, and S.U. Emerson (1998).  Genetic and experimental evidence for cross-species infection by the swine hepatitis E virus.  Journal of Virology.   72:9714-9721.

60.Halbur, P.G., M. Rothschild, B.J. Thacker, X.J. Meng, P.S. Paul, J. D. Bruna. (1998).  Differences in susceptibility of Duroc, Hampshire, and Meishan pigs to infection with a high virulence strain (VR2385) of porcine reproductive and respiratory syndrome virus (PRRSV).  Journal of Animal Breedings and Genetics115:181-189.

59.  Meng, X.J., P.G. Halbur, J.S. Haynes, T.S. Tsareva, J.D. Bruna, R.D. Royer, R.H. Purcell, and S.U. Emerson (1998).  Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.  Archives of Virology143:1405-1415

58.Meng, X.J., R.H. Purcell, P.G. Halbur, J.R. Lehman, D.M. Webb, T.S. Tsareva, J.S. Haynes, B.J. Thacker, and  S.U. Emerson (1997).  A novel virus in swine is closely related to the human hepatitis E virus.  Proceedings of the National Academy of Sciences USA   94:9860-9865.

57.Haynes, J.S., P.G. Halbur, T. Sirinarumitr, P. S. Paul, X.J. Meng, and E. L. Huffman (1997).  Temporal and morphologic characterization of the distribution of porcine reproductive and respiratory syndrome virus (PRRSV) by in situ hybridization in pigs infected with isolates of PRRSV that differ in virulence.Veterinary Pathology    34:39-43.

56.  Meng, X.J., P.S. Paul, P.G. Halbur, and M.A. Lum (1996).  Characterization of a high virulence U.S. isolate of porcine reproductive and respiratory syndrome virus in a continuous cell line, ATCC CRL11171.  Journal of Veterinary Diagnostic Investigation   8:374-381.

55.  Meng, X.J., P.S. Paul, I. Morozov, and P.G. Halbur (1996).  A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus.  Journal of General Virology   77:1265-1270.

54.Halbur, P.G., P.S. Paul, X.J. Meng, M.A. Lum, and J.A. Rathje (1996).  Comparative pathogenicity of nine U.S. porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a 5 week-old cesarean-derived-colostrum-deprived pig model.  Journal of Veterinary Diagnostic Investigation   8:11-20.

53.Halbur, P.G., P.S. Paul, M.L. Frey, J. Landgraf, K. Eernisse, X.J. Meng, J.J. Andrews, M.A. Lum, and J.A. Rathje (1996).  Comparison of the antigen distribution of two U.S. porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus.  Veterinary Pathology   33:159-170.

52.  Meng, X.J., P.S. Paul, P.G. Halbur, and I. Morozov (1995).  Sequence comparison of open reading frames 2 to 5 of low and high virulence U. S. isolates of porcine reproductive and respiratory syndrome viruses.  Journal of General Virology76:3181-3188.

51.Halbur, P.G., P.S. Paul, M.L. Frey, J. Landgraft, K. Eernisse, X.J. Meng, M.A. Lum, J.J. Andrews, and J.A. Rathje (1995).  Comparison of the pathogenicity of two U.S. porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus.  Veterinary Pathology   32:648-660.

50.  Meng, X.J., P.S. Paul, P.G. Halbur, and M.A. Lum (1995).  Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV):  implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe.  Archives of Virology  140:745-755.

49.Morozov, I., X.J. Meng, P.S. Paul (1995).Sequence analysis of open reading frames (ORF) 2 to 4 of the porcine reproductive and respiratory syndrome virus (PRRSV).  Archives of Virology140:1313-1319.

48.Halbur, P.G., L.D. Miller, P.S. Paul, X.J. Meng, E.L. Huffman, and J.J. Andrews (1995).  Immunohistochemical identification of porcine reproductive and respiratory syndrome virus (PRRSV) antigen in the heart and lymphoid system of three-week-old colostrum-deprived pigs.  Veterinary Pathology   32:200-204.

47.  Meng, X.J., P.S. Paul, and P.G. Halbur (1994).  Molecular cloning and nucleotide sequencing of the 3' terminal genomic RNA of porcine reproductive and respiratory syndrome virus.  Journal of General Virology   75:1795-1801.

46.Halbur, P.G., J.J. Andrews, E.L. Huffman, P.S. Paul, X.J. Meng, and Y. Niyo (1994).  Development of a streptavidin-biotin immunoperoxidase procedure for the detection of porcine reproductive and respiratory syndrome virus antigen in porcine lung.  Journal of Veterinary Diagnostic Investigation   6:254-257.

45.  Meng, X.J., P.S. Paul, E.M. Vaughn, and J.J. Zimmerman (1993).  Development of a radiolabeled nucleic acid probe for the detection of encephalomyocarditis virus infection in swine.  Journal of Veterinary Diagnostic Investigation   5:254-258.

44.Halbur, P.G., P.S. Paul, X.J. Meng, W. Hagemoser, M.A. Lum, and J.J. Andrews (1993).  Comparative pathogenicity of ten porcine reproductive and respiratory syndrome virus (PRRSV) isolates.  Veterinary Pathology   30:440.

43.Paul, P.S., P.G. Halbur, and X.J. Meng (1993).  Porcine reproductive and respiratory syndrome: An overview.  Journal of Clinical Veterinary Medicine (Japan)   11:19-28.