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Laboratory for Neurotoxicity Studies

LNS The Laboratory for Neurotoxicity Studies, located at the Virginia-Maryland Regional College of Veterinary Medicine, provides expertise in neuroscience, neurochemistry, neurotoxicology, neuropathology, and clinical neurology for studies done in animal models or in vitro. We are comprised of 7 Faculty members, 1 Post-doctoral fellow, 7 Graduate students, and 4 Technicians.

Participants
U.S. Army
Environmental Protection Agency
Private Industry
Results
100+ peer reviewed publications
Book chapters
Review articles
National advisory panels

What We Do

Drs. Jortner and Ehrich

The Laboratory for Neurotoxicity Studies at Virginia Tech offers unique opportunities for the study of specific problems of neurotoxicity and neuropathology associated with exposure to drugs and chemicals. The team of experienced scientists is capable of performing toxicological, physiological, biochemical, pathological, behavioral, and neurological investigations, which can be used for pathogenetic studies, product development, and safety assessment, including studies for which can be used for pathogenetic studies, product development, and safety assessment, including studies for which compliance with federal Good Laboratory Practices are required.

Research - Interdisciplinary basic and applied research provides comprehensive coverage of neurotoxic effects of such agents as pesticides, solvents, heavy metals, and mycotoxins. The laboratory has particular expertise with both in vivo and in vitro aspects of organophosphorus-induced delayed neuropathy.

Education - Graduate training in all areas of neurotoxicology is available, including graduate programs leading to master's and doctoral degrees in neurochemistry, neurology, and neuropathology. Trainees gain experience with Good Laboratory Practices to increase opportunities in laboratories of government and industry. Personnel training programs in behavioral assessment can be designed to meet client requirements.

Technical support and facilities - The lab is a 1,600-square-foot unit containing the latest equipment, including safety facilities to handle neurotoxic compounds. It is staffed by highly skilled, experienced laboratory technicians who work closely with the faculty members in our active research programs, bringing expertise in histology, electron microscopy, biochemistry, toxicology, tissue culture, and immunohistochemistry to these efforts.

Distinctions

* Marion Ehrich, diplomate of the American Board of Toxicology, has done extensive research on the acute metabolic and toxic effects of pesticides and mycotoxins and has an international reputation in mechanisms of organophosphorus ester-induced delayed neuropathy and for cell culture research.

* Bernard Jortner, diplomate of the American College of Veterinary Pathologists, has more than 25 years experience in neuropathology and neurotoxicology research.

Contact Information

Bernard Jortner, bjortner@vt.edu
Marion Ehrich, marion@vt.edu
Co-directors & Professors of Biomedical Sciences & Pathobiology
Laboratory for Neurotoxicity Studies
VA-MD Regional College of Veterinary Medicine
Virginia Tech (0442)
Blacksburg, VA 24061
Phone: (540) 231-4817
Fax: (540) 231-6033