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NAME S. Ansar Ahmed, DVM., Ph.D. |
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INSTITUTION AND LOCATION |
DEGREE (if
applicable) |
FIELD OF STUDY |
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The
Bangalore University |
B.S |
Chem.
Biol. Zool. |
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The
University of Agricultural Sciences |
BVSc
(DVM) |
Vet.
Med. Surg. |
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The
Murdoch University, Australia |
PhD |
Immunology
and Immunopathology |
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A. Positions and Honors.
§
Instructor in Veterinary Immunology and
Microbiology, Murdoch, Australia
§
Leukemia Foundation of America Fellow,
Division of Clinical Immunology, Department of Medicine, The University of
Texas Health Science Center at San Antonio
§
Research Instructor (’85-87), Research
Assistant Professor (’87-’89) Division of Clinical Immunology, Department of
Medicine, The University of Texas Health Center at San Antonio, Texas
Positions Held at the Virginia
Tech (Virginia Polytechnic Institute & State University)
§
Assistant Professor in Immunology
(Tenure track), Dept. of Pathobiology,Virginia-Maryland Regional College of
Veterinary Medicine, VPI and SU, Blacksburg, Virginia.
§
Tenured, Associate Professor, VMRCVM,
VPI & SU (VA Tech), Blacksburg, VA (’94)
§
Tenured, Professor of Immunology,
VMRCVM, VPI & SU (VA Tech), Blacksburg, VA (‘01)
§
Director, Center for Molecular Medicine
& Infectious Diseases, VMRCVM
HONORS:
DVM (BVSc):
Awarded all four academic
merit Gold Medals (1977):
Ø
UAS gold Medal for General Academic
Merit
Ø
Lions Club International Gold
Medal
Ø
Dr. S. Mohyuiddin’s Gold Medal for
Veterinary
Pathology
Ø
Dr. Rajkumar’s Gold Medal for
Veterinary
Medicine
Recipient of UAS MERIT Scholarship
(‘72-77)
Dr. Jawaharlal Nehru, National Award
(1977)
State
Government Award for Academic Merit (’78)
Ph.D.:
Ø
Upgraded from MS to Ph.D.
Ø
Murdoch University Scholarship Award (Australia)
Ø
External Examiners’ Evaluation
Category:
“Approved
with Highest Enthusiasm”(’84)
Ø
Murdoch University Travel Award (to
present
Papers at IVth International
Immunology meetings Paris (1980) and London (1980)
Post-doctoral: Leukemia
Research Fellowship from the Leukemia Society of America, Inc. (1983-85)
Selected Other Honors: Membership in Federal
Govt. Study Sections and Grant review Panels:
(1) ALTX-1 NIH, study section Ad
Hoc Member, 2001;
(2) ALTX-4 NIH study Section, Ad
Hoc Member, 2003;
(3) IRPG (Special Emphasis Panel)/ NIH - 2003;
(4) Special Emphasis Panel/ ZRG1 GMA-3 /NIH-2003;
(5) XNDA-NIH study
section, Ad Hoc Member 2004;
(6) ZRG Innate Immunity and
Inflammation/NIH, Nov. 04-05, 2004;
(7) NSF- Integrative
Animal Biology Program, Nov. 01, 2004;
(8) USDA/SBIR–2004.
External Reviewer
for Several Research Foundations::
(1)
The Blowitz-Ridgeway Foundation;
(2)
JW McLaughlin Foundation;
(3)
John Sealy Endowment Foundation);
(4)
ASPIRES Grant Review Panel, VT,
2004.
Research Awards and Other Academic Recognition:
(1) Smith Kline Beecham award
for Excellence in Research on Animal Health, 1994;
(2) Pfizer award for Research
Excellence- 2003;
(3) Member, Phi Zeta National Honor Society
and
(4) Early Promotion and Tenure,
1994;
(5) VMRCVM Excellence in Teaching Award, 1992;
(6) Early Promotion & Tenure, 1994;
(7) External reviewer for promotion and Tenure dossiers from several Universities.
Selected Recent
Invited Presentations: (Last 5 years only)::
(1) Keynote Speaker “Animal Models of Estrogen Effects on Immunity” presented at: ISNIM/
AAI, Experimental Biology’2001, Orlando, FL, 3/31/ 01; (2) Invited Speaker “Sex
hormones, Immunity & Autoimmunity” presented at: “ B cells and autoimmunity”, Satellite
Meeting to the 11th inter. Cong. of Immunol,7/19-21/01 Bergen,
Norway; (3) Panelist & Invited Speaker:,
“Focus on Sex Differences In Immunology & Autoimmunity”, Boston, 11/8/01; (4) Invited Speaker: ”Autoimmunity and Cell Signaling: Role
of estrogenic compounds., Vaccine Technology and Immune Responses, Riva, San
Vitale, Switzerland, April 3-5, 2002;
(5) Invited Speaker :“Molecular Regulation of interferong by estrogens: Implications to Immunity and Autoimmune Diseases”, University of Maryland
Seminar Series, College Park, MD., May
1, 2002; (6) Invited Speaker: “Estrogenic
Endocrine Disruptors and Immune Effects”, NIEHS meeting, Institute of
Advanced Learning and Research, Danville,VA., May 10, 2002; (7) Invited
Speaker: NIEHS Center “ Molecular
Signaling In Immune Cells by Estogenic Compounds”, Galveston, May 6, 2002,
TX (8) “ Estrogenic compounds
Regulate Interferong: Implications to Autoimmunity”,
Immunology Council Speaker at the John
Hopkins Center for Autoimmune Disease Research and PAHO/WHO Collaborating
Center for Autoimmune Disorders, November 5, 2002, Baltimore, Maryland; (9) Chairman
of the Break out Group, “Translation Research: Systemic Autoimmune
Diseases” at the Autoimmune Diseases and Environmental Factors,
Raliegh-Durham, NIEHS (Sponsored by NIAID and NIEHS). My role was to lead a group of nationally recognized scientists
to identify areas of research priorities, present these for discussion to all
attendees of the meeting and generate a document of recommendation of research
priorities to the NIH; (10) “The
Immune System – A Target for Environmental Estrogens" Presented at the Third International Conference on Sex
Hormones, Pregnancy, and the Rheumatic Diseases. Oct. 21-24, 2002, New Orleans; (11) Co-Chairman of Sex Hormones
and the Connective Tissue Diseases I:
The role of Gender and Hormones in connective tissue Disease” Third
International Conference on Sex Hormones, Pregnancy, and the Rheumatic
Diseases. Oct. 23, 2002, New Orleans; (12) “The immune system- the other
target tissue of estrogens:
Implications to immunity and autoimmunity” University of Virginia, June 19-20, 2003; (13) Chairman, “Translation
Research: Systemic Autoimmune Diseases” Break out Research Focus
Group at the Autoimmune Diseases and Environmental Factors, Raliegh-Durham,
NIEHS, (Sponsored by NIAID and NIEHS). Feb. 4, 2003; (14) National Institute of Aging – “Endocrine-Immune System
Interactions in Aging”, April 12-13, Potomac, MD.
Selected Peer-reviewed Publications (over 65):
Verthelyi
D and Ansar Ahmed S: Estrogen increases
the number of plasma cells and enhances their autoantibody production in
non-autoimmune C57BL/6J mice. Cellular Immunology, 189: 125-134, 1998
Boehm
GW, Sherman GF, Hoplight BJ, Hyde LA, Bradway DM, Galaburda AM, Ansar Ahmed S,
Denenberg VH. Learning in year-old
female autoimmune BXSB mice. Physiology and Behavior 64: 75-82, 1998
Ansar Ahmed S
and Talal, N: “Sex hormones, Immunity
and Autoimmune Diseases- an update”
In : A decade in Autoimmunity.
(ed. Y. Shoenfeld), Chapter 38;
325-329, 1998
Ansar Ahmed S, Hissong
BD, Verthelyi D, Donner K, Becker K, Karpuzoglu-Sahin, E: “Gender and Risk of
Autoimmune Diseases”. Environmental Health Perspectives. 107: 681-686,1999 (Invited Paper)
Walker
C, Ansar Ahmed
S, Brown T, Shuk-Mei Ho, Lucier G, Russo J,
Weigel N, Weise T, Vandenbergh J. Species,
Interindividual and Tissue Specificity in Endocrine Signaling Environmental
Health Perspectives, 107:
619-624, 1999 (Invited Paper)
Donner
kJ, Becker KM, Hissong BD, Ansar Ahmed S: Comparison of multiple assays for
kinetic detection of apoptosis in thymocytes exposed to dexamethasone or
diethylstilbestrol. Cytometry
35: 80-90, 1999
Gogal
RM, Ansar Ahmed
S, Smith S, Holladay SD: Mandates to develop non-mammalian models
for chemical immunotoxicity evaluations: Is fish a viable alternative to fish? Toxicology
Letters 106: 89-92,1999
Gogal
RM Jr., Ansar
Ahmed S, Walsh JE, Holladay SD., Galaburda AM, Rosen GD: Induced
minor malformations in the neocortex of normal mice do not alter immunological
functions. Immunological Investigations, 29 (3) 299-318, 2000
Ansar Ahmed S:
The immune system as a potential target for environmental estrogens (endocrine
disruptors): An area of growing importance. Toxicology ,150: 191-206, 2000
Ansar Ahmed S:
Should humoral immunity exclusively mean antibodies? A new expanded definition
to reflect a subspecialty of immunology. Immunology Letters 75:89-90,
2001
Karpuzoglu-Sahin
E, Zhi-jun, Yin, Sriranganathan N, Ansar Ahmed S: Effects of long-term estrogen
treatment on interferon-g,
interleukin 2, and interleukin 4 gene expression and protein synthesis in
spleen and thymus of normal C57BL/6 mice Cytokine 14 (4) 208-217, 2001.
Karpuzoglu-Sahin
E, Hissong, BD, Ansar
Ahmed S: Interferon-g levels are up-regulated by 17-b-estradiol and
diethylstilbestrol Journal of Reproductive Immunology
, 52: 113-127, 2001
Rosypal AC, Lindsay, DL, Duncan, Jr. R, Ansar Ahmed S, Zajac, AM and Dubey JP: " Mice lacking the gene for
inducible or endothelial nitric oxide are resistant to sporocyst-induced Sarcocystis neurona Infections . Veterinary
Parasitology 103: 315-321, 2002
Calemine,
JB., Gogal, RM., Jr., Lengi, A., Sponenberg, P., Ansar Ahmed S Immunomodualtion by
diethylstilbestrol is does and gender
related: Effects on thymocyte apoptosis and mitogen-induced proliferation. Toxicology:
178: 101-118, 2002
Calemine,
JB., Zelenka, J.,Lengi, A., Ansar Ahmed S: The immune system of geriatric mice is modulated by estrogenic
compounds (Diethylstilbestrol, Genestien, a-Zearalanol): Effects on mRNA and
protein.
Toxicology, 194: 115-128,
2003
Witonsky,
S., Gogal, RM., Jr., Buechner-Maxwell, V., Ansar Ahmed S. The immunological analysis on
horse peripheral blood samples stored for twenty-four hours. American
Journal of Veterinary Research, American Journal of Vet Research.
Aug; 64(8): 1003-9, 2003
Blaylock
BL, Ansar Ahmed
S, and Holladay SD Prenatal Immunotoxicant Exposure and Autoimmune
Disease. In: Developmental
Immunotoxicology. Editor, S.D. Holladay. CRC Press LLC, Boca Raton, FL.,
2004. (In press)
Karpuzoglu-Sahin
E, Gogal, RM. Jr., Hardy, C., Ansar Ahmed S. Short-term administration of 17-bestradiol in
outbred mice induced changes in lymphoid organ, but not reproductive organ. Immunological
Investigations (In Press) 2004
Ansar Ahmed S Karpuzoglu-Sahin E. “Estrogen,
Interferon-gamma, and Lupus” In: Molecular Autoimmunity. Edited by:
M. Zouali, Kluwer Academic Publshers, New York, (In press) 2004 (Invited
Paper)
Original papers
that are cited in over 100 peer-reviewed publications
(Source: Institute for Scientific Information, Web of
Science, Citation Databases):
Cited
in 426 publications -Ansar Ahmed S, Penhale WJ, Talal N: “Sex hormones, Immune responses and
Autoimmune responses: Mechanisms of Sex Hormone Action”. American Journal of Pathology 121:5
31-559, 1985.
Cited
in 311 publications -Ansar Ahmed S,
Gogal, R.M. Jr., Walsh, J.E. A new rapid and simple non-radioactive assay to
monitor and determine the proliferation of lymphocytes: An alternative to 3H-thymidine
incorporation assay.
Journal of Immunological Methods
170: 211-224, 1994.
Cited
in 122 publications- Ansar Ahmed S,
Dauphinee MJ, Talal, N.: Effect of short term administration of sex hormones on
normal and autoimmune mice.Journal of Immunology 134: 204-210,1985 (
Cited in 112 Publications-Lucas
JA, Ansar
Ahmed S, Casey ML, MacDonald PC: Prevention of
autoantibody formation and prolonged survival in New-Zealand black New-Zealand
white F1-mice fed dehydroisoandrosterone Journal Of Clinical Investigation
75 (6): 2091-2093 1985.
STUDIES SUPPORTED IN PART BY GRANTS FROM THE FOLLOWING AGENCIES:
NIEHS/NIH
NIH/NIAID
NIH/NICHD
NIH /NCRR
ASPIRES, Virginia Tech University
Competitive Program
USDA/AH&D Federal Govt. formula
Funds;
USDA/AH&D Federal Govt. formula
Funds
Lupus Foundation of America
Leukemia Foundation of America
Arthritis Foundation