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Research Awards

Grant Funding Announcement

Title: A chicken model to study HEV pathogenesis

Signficance: The lack of a practical animal model for HEV is a major obstacle for understanding the mechanism of HEV pathogenesis. This project will utilize a novel chicken model system to understand the pathogenesis of HEV, and the data from this project will help devise preventive and control strategies against HEV.

PI: X.J. Meng
CO-I: F.W. Pierson, T. LeRoith, Y.W. Huang

Total Award: $1,266,300
    Direct: $800,000
    Indirect: $466,300

Duration of Award: 03/01/2008 to 02/30/2012

Funding Agency: NIAID, NIH

Grant Funding Announcement

Title: Mechanism of hepatitis E virus replication and pathogenesis

Significance: The lack of knowledge on HEV biology and pathogenesis has greatly hindered the development of a vaccine against HEV. This project will delineate the structural and functional relationship of HEV genes using reverse genetics and animal models, and the results will aid in the development of a live-attenuated vaccine against this important but extremely understudied human pathogen.

PI: X.J. Meng
CO-I: P.G. Halbur, Y.W. Huang

Total Award: $1,561,797
    Direct: $1,000,000
    Indirect: $561,797

Duration of Award: 03/01/2008 to 02/30/2012

Funding Agency: NIAID, NIH