Biomedical Sciences & Pathobiology Faculty

Hehuang “David” Xie, PhD

Associate Professor
Epigenomics and Computational Biology
Department of Biomedical Sciences & Pathobiology

Education

  • 2003
    Ph.D., Genetics Program
    The University of Iowa
    Iowa City, IA
  • 2003
    Master of Science, Computer Science
    The University of Iowa
    Iowa City, IA
  • 1997
    Master of Science
    Shanghai Institute of Cell Biology
    Chinese Academy of Science
  • 1994
    Bachelor of Science, Genetics
    Sichuan University
    China

Research Interests

  • Neuro-epigenetics
  • Cancer and stem cell epigenomics
  • Computation biology and bioinformatics
  • Biotechnology and systems biology

Research Focus

Our group is particularly interested in strategies to assess epigenetic variation within and between cell populations, and to reveal transcription factors and gene networks controlling epigenetic dynamics during normal development and diseases. The term “epigenetic” mainly refers to histone modifications and DNA methylation, which are alternative ways to control gene expression while maintaining the nucleotide sequence of the genome. In other words, epigenetic changes allow cells with identical genomic content to demonstrate distinct phenotypes.

Learn more about research in Dr. Xie's Epigenomics and Computational Biology Laboratory.

Publications

View publications on Hehuang "David" Xie's PubMed profile.

Professional Experience

  • 2016 – Present
    Associate Professor
    Department of Biomedical Sciences and Pathobiology
    Virginia-Maryland College of Veterinary Medicine
    Virginia Tech
    Blacksburg, VA
  • 2016 – Present
    Associate Professor
    Biocomplexity Institute of Virginia Tech
    Department of Biological Sciences
    Virginia Tech
    Blacksburg, VA
  • 2012 – 2016
    Research Associate Professor
    Biocomplexity Institute of Virginia Tech
    Department of Biological Sciences
    Virginia Tech
    Blacksburg, VA
  • 2005 – 2012
    Research Assistant Professor
    Cancer Biology and Epigenomics Program
    Children's Memorial Research Center
    Department of Pediatrics, Feinberg School of Medicine
    Northwestern University
    Evanston, IL
  • 2004 – 2005
    Post/Doctoral Research Associate
    The University of Minnesota
    Advisor: Dr. Scott C. Fahrenkrug
  • 2003 – 2004
    Post/Doctoral Research Associate
    The University of Iowa
    Advisor: Dr. Bento Soares
    Iowa City, IA
  • 1998 – 2003
    Graduate Research Assistant
    The University of Iowa
    Advisor: Dr. Bento Soares
    Iowa City, IA

Professional Memberships

  • Member, International Society of Computational Biology