Biomedical Sciences & Pathobiology Faculty

Elankumaran Subbiah, BVSc, MVSc, PhD, Diplomate ACVM

Associate Professor
Virology
Department of Biomedical Sciences & Pathobiology
Center for Molecular Medicine and Infectious Disease

Education

  • 1996
    PhD, Veterinary Microbiology
    Madras Veterinary College
  • 1989
    MVSc, Veterinary Microbiology
    Madras Veterinary College
  • 1984
    BVSc, Veterinary Medicine
    Madras Veterinary College

Board Certification

  • 2003
    Diplomate, American College of Veterinary Microbiologists, Virology

Research Interests

Broad Research Interests:

  • Negative strand RNA viruses, their structure and function, pathogenesis, and control of diseases produced by them
  • RNA virotherapy of invasive tumors
  • Development of novel, non-invasive immunization strategies for control of viral diseases
  • Emerging viral diseases

Current Research Areas:

  • Develop recombinant Newcastle disease virus (NDV) as an oncolytic agent
  • Molecular basis of interspecies transmission of influenza A viruses with emphasis on swine influenza virus
  • Viral vectored vaccines for emerging viral diseases

Professional Experience

  • 2012 – Present
    Associate Professor
    Biomedical Sciences & Pathobiology
    Center for Molecular Medicine and Infectious Disease
    Virginia-Maryland College of Veterinary Medicine
    Virginia Tech
    Blacksburg, VA
  • 2006 – 2012
    Assistant Professor
    Biomedical Sciences & Pathobiology
    Center for Molecular Medicine and Infectious Disease
    Virginia-Maryland College of Veterinary Medicine
    Virginia Tech
    Blacksburg, VA
  • 2004 – 2006
    Research Assistant Professor
    Virginia-Maryland College of Veterinary Medicine
    University of Maryland
    College Park, MD
  • 1999 – 2004
    Faculty Research Associate
    College of Agriculture and Natural Resources
    Virginia-Maryland College of Veterinary Medicine
    University of Maryland
    College Park, MD
  • 1989 – 1999
    Job Title
    Name of Department
    Name of Institution
    City, ST, USA
  • 1987 – 1989
    Assistant Professor
    Central University Laboratory
    Center for Animal Health Studies
    Tamil Nadu Veterinary and Animal Sciences University
  • 1984 – 1987
    Assistant Manager
    Tamil Nadu Co-operative Milk Producer's Union Ltd.
    Veterinary Medicine - Veterinary Services

Professional Memberships

  • American Association of Veterinary Immunologists
  • American Association for the Advancement of Science
  • American Association of Avian Pathologists
  • American College of Veterinary Microbiologists
  • American Society for Virology
  • American Association of Cancer Research
  • American Geophysical Union

Selected Publications

  1. Elankumaran, S., D. D. Rockemann and S. K. Samal. 2006. Newcastle disease virus exerts oncolysis both by intrinsic and extrinsic caspase-dependent pathways of cell death Journal of Virology 80: 7522-7534.
  2. DiNapoli, J. M., A. Kotelkin, L. Yang, S. Elankumaran, B.R. Murphy, S. K. Samal, P. L. Collins, A. Bukreyev. 2007. Newcastle disease virus, a highly host-range-restricted virus, as a vaccine vector for intranasal immunization against emerging pathogens. Proceeding of the National Academy of Science 104: 9788-9793.
  3. Dinapoli, J.M, L. Yang, Suguitan, A Jr, S. Elankumaran, D. W. Dorward, B. R. Murphy, S. K. Samal, P. L. Collins, and A. Bukreyev. 2007. Immunization of primates with a Newcastle disease virus-vectored vaccine via the respiratory tract induces a high titer of serum neutralizing antibodies against highly pathogenic avian influenza virus. Journal of Virology 81:11560-11568.
  4. Kishimoto TK, K. Viswanathan, T. Ganguly, S. Elankumaran, S. Smith, K. Pelzer, J. C. Lansing, N. Sriranganathan, G. Zhao, Z. Galcheva-Gargova, A. Al-Hakim, G. S. Bailey, B. Fraser, S. Roy, T. Rogers-Cotrone, L. Buhse, M. Whary, J. Fox, M. Nasr, G. J. Dal Pan, Z. Shriver, R. S. Langer, G. Venkataraman, K. F. Austen, J. Woodcock, R. Sasisekharan. 2008. Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System. New England Journal of Medicine 358: 2457-2467.
  5. Qiao, D., B.H. Janke. S. Elankumaran. 2010. Complete genome sequence and pathogenicity of two swine parainfluenzavirus 3 isolates from pigs in the United States. Journal of Virology 84: 686-694.
  6. Elankumaran, S., V. Chavan, D. Qiao, R. Shobana, G. Moorkanat and S. K. Samal. 2010. Type I interferon sensitive recombinant Newcastle disease virus for oncolytic virotherapy. Journal of Virology 84: 3835-3844. (5.15). PMID: 20147405
  7. Yang, W. S. Elankumaran and L. Marr. 2011. Concentrations and size distributions of airborne influenza A viruses measured indoors at a health centre, a day-care centre and on aeroplanes. Journal of Royal Society Interface 8: 1176-1184.
  8. Biswas, M., S. R. Kumar, A. Allen, W. Yong, R. Nimmanapalli, S. K. Samal and S. Elankumaran. 2012. Cell type specific innate immune response to oncolytic Newcastle disease virus. Viral Immunology. 25 (4): 268-276 (Journal Cover Art).
  9. Biswas, M., J. B. Johnson, S. R. Kumar, G. D. Parks and S. Elankumaran. 2012. Incorporation of host complement regulatory proteins into Newcastle disease virus enhances complement evasion. Journal of Virology September 12 (Epub 2012 Sep 12).
  10. Yang, W. S. Elankumaran and L. C. Marr. 2012. Relationship between humidity and Influenza A viability in droplets and implications for Influenza's seasonality. PLoS One. 2012;7 (10): e46789. (Epub 2012 Oct 3).