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DBSP Faculty

YongWoo Lee

YongWoo Lee, MS, PhD

Assistant Professor
Cellular and Molecular Biology
Department of Biomedical Sciences & Pathobiology
 
e-mail: ywlee@vt.edu
 
Laboratory of Vascular Biology: http://www.vascular.sbes.vt.edu


Education

1994-1997 Ph.D., Biological Sciences
Korea Advanced Institute of Science and Technology (KAIST)
Taejon, South Korea
1986-1988 M.S., Biochemistry
Yonsei University
Seoul, South Korea
1982-1986 B.S., Applied Biology and Chemistry
Seoul National University
Seoul, South Korea

Research Interests

  • Cellular and molecular mechanisms of inflammatory vascular disease
  • NanoMedicine: Biomedical applications of nanotechnology
     

Professional Experience

2004-present Primary Faculty
School of Biomedical Engineering & Sciences
Virginia Tech-Wake Forest University
2002-2004 Assistant Professor, Neurosurgery
University of Kentucky
2001-2002 Research Associate, Neurosurgery
University of Kentucky
1999-2001 Postdoctoral Scholar, Neurosurgery
University of Kentucky
1988-1998 Senior Investigator
Lotte Group R&D Center
Seoul, South Korea

SelectedPublications

  1. Lee YW, Eum SY, Nath A, Toborek M. Estrogen-mediated protection against HIV Tat protein-induced inflammatory pathways in human vascular endothelial cells. Cardiovascular Research. 2004;63:139-148.
  2. Lee YW, Eum SY, Chen KC, Hennig B, Toborek M. Gene expression profile in interleukin-4-stimulated human vascular endothelial cells. Molecular Medicine. 2004;10:19-27.
  3. Flora G, Pu H, Lee YW, Ravikumar R, Nath A, Hennig B, Toborek M. Proinflammatory synergism of ethanol and HIV-1 Tat protein in brain tissue. Experimental Neurology. 2005;191:2-12.
  4. Lee YW, Hirani AA, Kyprianou N, Toborek M. Human immunodeficiency virus-1 Tat protein up-regulates interleukin-6 and interleukin-8 expression in human breast cancer cells. Inflammation Research. 2005;54:380-389.
  5. Lee YW, Hirani A. A. Role of interleukin-4 in atherosclerosis. Archives of Pharmacal Research. 2006;29:1-15.
  6. Eum SY, Lee YW, Hennig B, Toborek M. The interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells. Molecular Cancer Research. 2006;4:361-370.
  7. Kreke MR, Sharp LA, Lee YW, Goldstein AS. Effects of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells. Tissue Engineering Part A. 2008;14:529-537.
  8. Lee YW, Lee WH. Protective effects of genistein on pro-inflammatory pathways in human brain microvascular endothelial cells. Journal of Nutritional Biochemistry. 2008;19:819-825.
  9. Hong JH, Omur-Ozbek P, Stanek BT, Dietrich AM, Duncan SE, Lee YW, Lesser G. Taste and odor abnormalities in cancer patients. Journal of Supportive Oncology. July 2008; Accepted for publication.
  10. Sharp LA, Lee YW, Goldstein AS. Effect of low-frequency pulsatile flow on expression of osteoblastic genes by bone marrow stromal cells. Annals of Biomedical Engineering. December 2008; Accepted for publication.