DBSP
Roster  DBSP Departments VA-MD Vet Med

DBSP Faculty

Xin M. Luo

Xin M. Luo, Ph.D.

Assistant Professor
Immunology
Department of Biomedical Sciences & Pathobiology

e-mail: xinluo@vt.edu

Dr. Luo's Laboratory website


Education

2006 Ph.D., Immunology
Pennsylvania State University-University Park
2001 M.S., Nutritional Sciences
Pennsylvania State University-University Park
1998 B.S., Biochemistry & Molecular Biology
Peking University, China

Research Interests

The research interests in the Luo Laboratory are immunological and microbial regulation of autoimmunity and immunodeficiency. On the immunological side, we are interested in the roles of dendritic cells in inflammation; while on the microbial side, we focus on how commensal bacteria in the gut affect the host immune system, and vice versa. We utilize murine models and human patient samples to study various diseases including systemic lupus erythematosus and primary immunodeficiencies.


Professional Experience

2012-present Assistant Professor, Immunology
Department of Biomedical Sciences and Pathobiology
VA-MD Regional College of Veterinary Medicine
Virginia Tech, Blacksburg, VA
Sept-Dec 2011 Scientist II, Cell Signaling Technology
2010-2011 Research Scientist
Division of Biology
California Institute of Technology
2005-2010 Postdoctoral Fellow
Division of Biology
California Institute of Technology
Mentor: David Baltimore (Nobel Laureate)

Professional Membership

  • American Association of Immunologists (AAI)

Selected Publications

  1. Luo XM, Lei MYY, Feidi RA, West AP, Balazs AB, Bjorkman PJ, Yang L, Baltimore D. (2010) Dimeric 2G12 as a potent protection against HIV-1. PLoS Pathogens 6(12): e1001225.
  2. Luo XM, Maarschalk E, O'Connell RM, Wang P, Yang L, Baltimore D. (2009) Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes. Blood 113(7): 1422-1431.
  3. Luo XM, Ross AC. (2006) Retinoic acid exerts dual regulatory actions on the expression and nuclear localization of interferon regulatory factor-1. Experimental Biology and Medicine 231(5): 619-631.
  4. Luo XM, Ross AC. (2005) Physiological and receptor-selective retinoids modulate interferon-γ signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1. Journal of Biological Chemistry 280(43): 36228-36236.
  5. Luo XM, Fosmire GJ, Leach RM Jr. (2002) Chicken keel cartilage as a source of chondroitin sulfate. Poultry Science 81(7): 1086-1089.