Roster  DBSP Departments VA-MD Vet Med

DBSP Faculty

Xin M. Luo

Xin M. Luo, Ph.D.

Assistant Professor
Department of Biomedical Sciences & Pathobiology

e-mail: xinluo@vt.edu

Dr. Luo's Laboratory website


2006 Ph.D., Immunology
Pennsylvania State University-University Park
2001 M.S., Nutritional Sciences
Pennsylvania State University-University Park
1998 B.S., Biochemistry & Molecular Biology
Peking University, China

Research Interests

  • Regulatory mechanisms of Type I interferon response in plasmacytoid dendritic cells
  • Roles of Type I interferons and plasmacytoid dendritic cells in autoimmunity
  • Fundamental mechanisms of human B cell development
  • Genetic engineering of antigen-specific immunity against human pathogens

Professional Experience

2012-present Assistant Professor, Immunology
Department of Biomedical Sciences and Pathobiology
VA-MD Regional College of Veterinary Medicine
Virginia Tech, Blacksburg, VA
Sept-Dec 2011 Scientist II, Cell Signaling Technology
2010-2011 Research Scientist
Division of Biology
California Institute of Technology
2005-2010 Postdoctoral Fellow
Division of Biology
California Institute of Technology
Mentor: David Baltimore (Nobel Laureate)

Professional Membership

  • American Association of Immunologists (AAI)

Selected Publications

  1. Luo XM, Lei MYY, Feidi RA, West AP, Balazs AB, Bjorkman PJ, Yang L, Baltimore D. (2010) Dimeric 2G12 as a potent protection against HIV-1. PLoS Pathogens 6(12): e1001225.
  2. Luo XM, Maarschalk E, O'Connell RM, Wang P, Yang L, Baltimore D. (2009) Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes. Blood 113(7): 1422-1431.
  3. Luo XM, Ross AC. (2006) Retinoic acid exerts dual regulatory actions on the expression and nuclear localization of interferon regulatory factor-1. Experimental Biology and Medicine 231(5): 619-631.
  4. Luo XM, Ross AC. (2005) Physiological and receptor-selective retinoids modulate interferon-γ signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1. Journal of Biological Chemistry 280(43): 36228-36236.
  5. Luo XM, Fosmire GJ, Leach RM Jr. (2002) Chicken keel cartilage as a source of chondroitin sulfate. Poultry Science 81(7): 1086-1089.