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Yasuhiro Suzuki, PhD, DMScAssociate Professor |
| 1989 | D.M.Sc. Jikei University, Tokyo, Japan |
| 1982 | Ph.D. Tokyo University, Tokyo, Japan |
| 1976 | B.S. Tokyo University, Tokyo, Japan |
My laboratory has been investigating the mechanism of host-pathogen interactions in infection with Toxoplasma gondii, an obligate intracellular protozoan parasite. Our recent focus of research is the molecular immunopathogenesis of cerebral toxoplasmosis. Toxoplasmic encephalitis (TE) has been a major opportunistic infectious disease in immunocompromised patients, such as those with AIDS and organ transplant recipients. In addition, TE is an excellent model for analyzing the mechanism of host defense in the brain. We have developed murine models of TE and found three factors critical in determining the host resistance to this disease. These are: IFN-g-mediated immune response, the genetic background of the host, and the strain of T. gondii. We are trying to obtain understanding of the molecular basis of host resistance to development of TE, by defining how the IFN-g-mediated immune response functions in the brain and how the genetic background of the host and the strain of T. gondii affect the immune response.
For more information, please see Dr. Suzuki's Immunology Lab web site.
| 2001-present | Associate Professor Center for Molecular Medicine and Infectious Deseases (CMMID) Department of Biomedical Sciences & Pathobiology Virginia-Maryland Regional College of Veterinary Medicine Virginia Tech, Blacksburg, VA |
| 1998-2001 | Consulting Assistant Professor Division of Infectious Diseases and Geographic Medicine Department of Medicine, Stanford University School of Medicine Stanford, CA |
| 1993-2001 | Senior Research Associate Research Institute, Palo Alto Medical Foundation Palo Alto, CA |
| 1994-1997 | Senior Research Associate Division of Infectious Diseases and Geographic Medicine Department of Medicine, Stanford University School of Medicine Stanford, CA |
| 1993-1994 | Research Associate Division of Infectious Diseases and Geoggraphic Medicine Department of Medicine, Stanford University School of Medicine Stanford, CA |