Case Outline

Goal and Learning Objectives


Clinical Scenario: Chronic Granulomatous Disease

1.   What Is The Basis Of This Condition?
2.   What Metabolic Deficiencies Can Cause It?
3.   What Is The Role Of NADPH Oxidase In Neutrophils?
4.   Is The Disease Explained By Only One Molecular defect?
5.   Key Facts About Chronic Granulomatous Disease (CGD)
6.   Infections With Catalase-Positive Bacteria
7.   Bacterial Pneumonia In CGD
8.   What Did The Clinical Test Reveal?
9.   Nitroblue Tetrazolium (NBT) Tests
10. Chemiluminescence Assay